32395-29-2Relevant academic research and scientific papers
Gold-Catalyzed Access to Isophosphinoline 2-Oxides
Ayad, Tahar,Boosaliki, Hooriye,Burilov, Alexander R.,Chacktas, Geraud,Darvish, Fatemeh,Hariri, Mina,Lebibi, Jacques,Mengue Me Ndong, Karen-Pacelye,Mwande-Maguene, Gabin,Pirat, Jean-Luc,Sechet, Nora,Tran Do, Minh Loan,Virieux, David
, p. 7813 - 7824 (2021/06/25)
Gold(I)-catalyzed reactions of electron-poor alkynes are still a challenging process. A straightforward synthesis of phosphorus-based heterocycles, namely, 2-phenyl 1H-isophosphinoline 2-oxides 1, is reported. The reaction used PPh3AuCl precatalyst in com
Practical synthesis of chiral vinylphosphine oxides by direct nucleophilic substitution. Stereodivergent synthesis of aminophosphine ligands
Oliana, Marco,King, Frank,Horton, Peter N.,Hursthouse,Hii, King Kuok
, p. 2472 - 2479 (2007/10/03)
A practical synthesis of optically pure alkylphenylvinylphosphine oxides is described, utilizing a nucleophilic displacement at phosphorus to install the vinyl moiety. The products were used to prepare classes of P-stereogenic aminophosphine (PN) and aminohydroxyphosphine (PNO) ligands. Stereocontrol can be exerted at various stages of the synthesis, to provide specific combinations of chirality in the final product. The effect of the stereogenic phosphorus and match-mismatch of chiralities of PNO ligands were examined in the asymmetric ruthenium-catalyzed hydrogen transfer reduction of three aryl ketones.
Nucleophilic Substitution in Benzylic Thiophosphinyl and Thiophosphonyl Chlorides: the Contribution of Elimination-Addition Pathways with Methylenethiooxophosphorane (Thiophosphene) Intermediates
Coogan, Michael P.,Harger, Martin J. P.
, p. 2101 - 2108 (2007/10/02)
For the reactions of ArCH2P(S)(Ph)Cl and ArCH2P(S)(NMe2)Cl with Et2NH, changing ArCH2 from benzyl to 4-nitrobenzyl increases the rates of substitution by factors of 80 and >103, respectively, and reduces markedly the ability to discriminate bet
Kinetic Study on the Alkaline Hydrolysis of Some Tetracoordinate PV Esters of 2,4-Dinitrophenol
Cevasco, Giorgio,Thea, Sergio
, p. 1103 - 1106 (2007/10/02)
The alkaline hydrolysis of 2,4-dinitrophenyl esters of benzylphosphinic, benzylphosphonic and benzylphosphonamidic acid does not proceed through a carbanion-promoted dissociative mechanism, a possible alternative pathway to the usual SN2(P) process; this is a further indication of the clear preference for associative displacement at phosphorous.
