32398-66-6

Basic information

• Product Name: Benzenemethanol, a-1-propynyl-
• Synonyms: 4-hydroxy-4-phenyl-2-butyne;rac-1-phenylbut-2-yn-1-ol;1-hydroxy-1-phenylbut-2-yne;phenyl-1 butyne-2 ol-1;1-Phenyl-2-butyn-1-ol;(+/-)-1-phenyl-2-butynol
• CAS NO: 32398-66-6
• Molecular Formula: C10H10O
• Molecular Weight: 146.189
• Mol File: 32398-66-6.mol
• Article Data: 38

Chemical Properties

• Melting Point: 37 °C
• Boiling Point: 110 °C(Press: 0.8 Torr)
• Density: 1.068±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenemethanol, a-1-propynyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-1-propynyl-(32398-66-6)
• EPA Substance Registry System: Benzenemethanol, a-1-propynyl-(32398-66-6)

Safety Data

• Hazardous Substances Data: 32398-66-6(Hazardous Substances Data)

Upstream product

• 4529-04-8 1-propynyl lithium 
• 100-52-7 benzaldehyde 
• 74-99-7 prop-1-yne 
• 463-49-0 1,2-propanediene 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 74-88-4 methyl iodide 
• 108-05-4 vinyl acetate 
• 6710-62-9 1-phenyl-2-butyn-1-one 
• 58879-44-0 1-acetoxy-1-phenylbut-2-yne 
• 32904-84-0 4-hydroxy-4-phenyl-2-butynyl methyl ether 
• 693-04-9 butyl magnesium bromide 
• 14630-40-1 Bis(trimethylsilyl)ethyne 
• 590-14-7 1-bromo-1-propene 
• 61668-36-8 bromo-2 trimethylsilyloxy-1 propene-1 

Downstream Products

• 6710-62-9 1-phenyl-2-butyn-1-one 
• 1896-62-4 (E)-benzalacetone 
• 74785-06-1 (Z)-3-Iodo-1-phenyl-but-2-en-1-ol 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 93247-37-1 (3-cyclohexylbuta-1,2-dien-1-yl)benzene 
• 72014-10-9 3-methyl-2-methylene-1-phenyl-3-butenol 
• 108840-26-2 5-ethyl-2-methyl-4-phenylfuran-3-carboxylic acid ethyl ester 
• 18594-93-9 3-phenylamino-1-phenylbut-2-en-1-one 
• 18192-20-6 cis-1-Phenyl-1-trimethylsilyloxy-buten-⁽²⁾ 
• 937-53-1 (Z)-4-phenylbut-3-en-2-one 
• 1260635-85-5 C₁₉H₁₄O₃ 
• 15151-14-1 2-methyl-4-phenylpyrano[3,2-c]chromen-5(4H)-one 
• 1260635-76-4 C₁₆H₁₆O₂ 
• 1198272-66-0 (+/-)-4-[1-nitroeth-2-yloxy]-4-phenylbut-2-ene 

Relevant articles and documents

BCL-2 INHIBITOR

Disclosed herein is a compound of Formula (I) for inhibiting both Bcl-2 wild type and mutated Bcl-2, in particular, Bcl-2 G101V and D103Y, and a method of using the compound disclosed herein for treating dysregulated apoptotic diseases.

Rhodium-Catalyzed C?H Activation/Annulation Cascade of Aryl Oximes and Propargyl Alcohols to Isoquinoline N-Oxides

A β-hydroxy elimination instead of common oxidization to carbonyl group in secondary propargyl alcohols was successfully developed to form 2-benzyl substituted isoquinoline N-oxides by a Rhodium-catalyzed C?H activation and annulation cascade, in which moderate to excellent yields (up to 92%) could be obtained under mild reaction conditions, along with good regioselectivity, broad generality and applicability. (Figure presented.).

Au(I)-catalyzed cycloaddition pathways of non-terminal propargyl substrates

Novel chiral menthol-based pyridyl nitrone ligands were synthesized and Au(I) coordination of the ligands gave chiral Au(I)–nitrone complexes. 1H NMR studies of the gold(I) coordination experiments with nitrone ligands afforded a convenient method for monitoring complex formation. The catalytic effect of Au(I)–nitrone complexes, shown to tune catalytic systems to produce uncommon products, was evaluated in [2 + 2 + 2] cyclotrimerization and [2 + 4] cyclodimerization reactions of non-terminal propargyl acetals. Alternative gold(I)-catalyzed [2 + 2], [2 + 4] and [3 + 4] cycloaddition reaction pathways of non-terminal propargyl acetals with imine substrates gave a diverse range of N-heterocyclic products. The present screening study demonstrates the potential and the versatility of non-terminal propargyl acetals in gold(I)-catalyzed cycloaddition reactions.