32399-49-8

Usage

Uses

Used in Organic Synthesis:
2,4,6-Cycloheptatriene-1-carboxamide,N,N-dimethyl-(8CI,9CI) is used as a building block for the synthesis of more complex organic molecules. Its unique structure and functional groups make it a valuable component in the creation of new compounds with potential applications in various industries.
Used in Chemical Reactions:
2,4,6-Cycloheptatriene-1-carboxamide,N,N-dimethyl-(8CI,9CI) is used as a reagent in various chemical reactions. Its amide and dimethyl groups can participate in a range of reactions, allowing for the formation of new compounds with different properties and potential uses.

Upstream product

• 27332-37-2 ethyl cyclohepta-2,4,6-trienecarboxylate 
• 4440-40-8 cyclohepta-2,4,6-trienecarboxylic acid 
• 13612-59-4 cyclohepta-2,4,6-triene-1-carbonitrile 
• 32399-48-7 cycloheptatriene-7-carbonyl chloride 
• 124-40-3 dimethyl amine 

Downstream Products

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 113249-67-5 (R^*,R^*;S^*,S^*)-3-(Hydroxyphenylmethyl)-N,N-dimethyl-1,4,6-cycloheptatrien-1-carboxamid 
• 113249-68-6 (R^*,S^*;S^*,R^*)-3-(Hydroxyphenylmethyl)-N,N-dimethyl-1,4,6-cycloheptatrien-1-carboxamid 
• 68940-37-4 Lithium-8-(dimethylamino)heptafulven-8-olat 
• 113249-69-7 7-(Hydroxydiphenylmethyl)-N,N-dimethyl-1,3,5-cycloheptatrien-1-carboxyamid 
• 113249-70-0 3-(Hydroxydiphenylmethyl)-N,N-dimethyl-1,4,6-cycloheptatrien-1-carboxyamid 
• 113249-71-1 5-(Hydroxydiphenylmethyl)-N,N-dimethyl-1,3,6-cycloheptatrien-1-carboxyamid 

Relevant academic research and scientific papers

Ion pair acidities and aggregation of some amide and oxazoline enolates in THF

Equilibrium lithium ion pair acidities at 25 °C have been determined in THF for the following acetamides: N,N-dimethyl-(4-biphenylyl)acetamide (1) (19.69), N,N-diethyl-(4-biphenylyl)acetamide (2) (20.30), N,N-dimethyl- diphenylacetamide (3) (20.76), N,N-diethyl-diphenylacetamide (4) (21.99), and 1-(diphenylmethylcarbonyl)pyrrolidine (5) (21.08). These acidity data compare well with those previously reported for the corresponding cesium enolates. Lithium and cesium ion pair acidities in THF are reported for two oxazolines: 2-(4-biphenylylmethyl)oxazoline (6) (Li, 21.53; Cs, 25.49) and (E)-(4S,5R)- 2-(4-biphenylylmethyl)-4-methoxymethyl-5-phenyloxazoline (7) (Li, 20.10; Cs 24.21). Studies of their acidities over a wide range of concentrations indicate that all of the lithium and cesium enolates of 1-7 are essentially monomeric at concentrations ranging from 10-3 to 10-4 M. Traces of dimer were detected for the lithium enolates of amides 1 and 2 and for the cesium enolate of oxazoline 6. Their dimerization constants (M-1) were found to be about 450, 200, and 150, respectively. All of the other lithium and cesium enolate probably form small amounts of dimer, but the dimerization constant of -1 is below the limit of precision of our spectroscopic method.

Some stable substituted cycloheptatrienyl carbanions

The reaction of some 7-substituted cycloheptatrienes with KNH2 in liquid ammonia is described.In several cases stable carbanions are formed.Their NMR spectra are consistent with a non-planar pentadienyl-like structure.A comparison of the 1H-NMR spectra of 10 and 11 shows the paratropic character of the cycloheptatrienyl anions.