324057-41-2

Upstream product

• 223526-92-9 ethyl 2-(2-propenyl-4-toluenesulfonylamino)benzoate 
• 223526-78-1 ethyl 2-(4-methylphenylsulfonamido)benzoate 
• 87-25-2 2-ethoxycarbonylaniline 
• 134-20-3 2-carbomethoxyaniline 
• 50998-74-8 methyl N-tosylanthranilate 
• 928708-41-2 methyl 2-{[(4-methylphenyl)sulfonyl](2-propen-1-yl)amino}benzoate 

Downstream Products

• 1352812-33-9 C₁₇H₁₅NO₃S 
• 30504-93-9 3-methyl-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-quinolin-4-one 
• 1454663-84-3 diethyl ((6-tosyl-5,6-dihydrobenzo[h][1,6]naphthyridin-2-yl)methyl)phosphonate 
• 1454663-83-2 C₂₃H₂₂N₂O₄S 
• 1454663-82-1 2-(4-bromobenzyl)-6-tosyl-5,6-dihydrobenzo[h][1,6]naphthyridine 
• 1454663-77-4 2-oxo-4-(4-oxo-1-tosyl-1,2,3,4-tetrahydroquinolin-3-yl)butyl pivalate 
• 1454663-75-2 diethyl (2-oxo-4-(4-oxo-1-tosyl-1,2,3,4-tetrahydroquinolin-3-yl)butyl)phosphonate 
• 1454663-74-1 ethyl 3-oxo-2-((4-oxo-1-tosyl-1,2,3,4-tetrahydroquinolin-3-yl)methyl)butanoate 
• 1454663-73-0 ethyl 3-oxo-5-(4-oxo-1-tosyl-1,2,3,4-tetrahydroquinolin-3-yl)pentanoate 
• 1454663-72-9 3-(2-methyl-3-oxopentyl)-1-tosyl-2,3-dihydroquinolin-4(1H)-one 
• 1454663-71-8 3-(4-(4-bromophenyl)-3-oxobutyl)-1-tosyl-2,3-dihydroquinolin-4(1H)-one 
• 1454663-70-7 3-(4-chloro-3-oxobutyl)-1-tosyl-2,3-dihydroquinolin-4(1H)-one 
• 1454663-69-4 3-(3-oxobutyl)-1-tosyl-2,3-dihydroquinolin-4(1H)-one 
• 1454663-49-0 diethyl (2-((N-allyl-4-methylphenyl)sulfonamido)benzoyl)phosphonate 

Relevant academic research and scientific papers

Overcoming the Deallylation Problem: Palladium(II)-Catalyzed Chemo-, Regio-, and Stereoselective Allylic Oxidation of Aryl Allyl Ether, Amine, and Amino Acids

We report herein a Pd(II)/bis-sulfoxide-catalyzed intramolecular allylic C-H acetoxylation of aryl allyl ether, amine, and amino acids with the retention of a labile allyl moiety. Mechanistically, the reaction proceeds through a distinct double-bond isomerization from the allylic to the vinylic position followed by intramolecular carboxypalladation and the β-hydride elimination pathway. For the first time, C-H oxidation of N-allyl-protected amino acids to furnish five-membered heterocycles through 1,3-syn-addition is established with excellent diastereoselectivity.

Cobalt-catalyzed cyclization with the introduction of cyano, acyl and aminoalkyl groups

An efficient synthesis of carbo-and heterocycles using CC, CO and CN bonds under cobalt catalysis is described. The substituents on olefins are key for controlling the regio-and chemoselectivity in the initial hydrogen atom transfer step and quaternary carbons are efficiently constructed under mild conditions. Cyclopropane cleavage and tandem cyclization give highly functionalized bicyclic skeletons in a single operation.

Oxidative cyclization of alkenoic acids promoted by AgOAc

Alkenoic acids derived from salicylic acid and analogues undergo an unexpected oxidative cyclization process triggered by AgOAc leading to 4H-benzo[d][1,3]dioxin-4-ones. The process is affected by the substitution on the aryl and the allyl units.

Regioselective silver-mediated Kondakov-Darzens olefin acylation

Enone construction: A silver-mediated olefin acylation reaction is described, in which five-, six-, and -seven-membered rings, tetrasubstituted olefins, bridged bicycles, spirocycles, and benzoxepinones are prepared. Highly selective intermolecular reactions are coupled to a Nazarov cyclization for the effective preparation of cyclopentenones, including the core of modhephene (see scheme). Copyright