3243-04-7

Basic information

• Product Name: 1-Indolizinecarbonitrile, 2-methyl-
• CAS NO: 3243-04-7
• Molecular Formula: C10H8N2
• Molecular Weight: 156.187
• Mol File: 3243-04-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Indolizinecarbonitrile, 2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Indolizinecarbonitrile, 2-methyl-(3243-04-7)
• EPA Substance Registry System: 1-Indolizinecarbonitrile, 2-methyl-(3243-04-7)

Safety Data

• Hazardous Substances Data: 3243-04-7(Hazardous Substances Data)

Usage

Heterocyclic compound

Contains both carbon and nitrogen atoms This chemical is a heterocyclic compound, meaning it has a ring structure containing both carbon and nitrogen atoms in its composition.

Unique structure and properties

Useful for studying chemical and biological processes The compound's unique structure and properties make it valuable for investigating various chemical and biological processes.

Potential hazards and risks

Handle with care It is important to handle and use 1-Indolizinecarbonitrile, 2-methylwith caution, as it may have potential hazards and risks associated with its use.

Upstream product

• 4786-20-3 crotononitrile 
• 6266-23-5 1-(carboxymethyl)pyridinium chloride 
• 110-86-1 pyridine 
• 768-18-3 2-methylindolizine 
• 870-30-4 isocyanatophosphonic dichloride 

Downstream Products

• 1394827-54-3 2-methyl-3-phenylindolizine-1-carbonitrile 
• 1394827-65-6 2-methyl-3-(phenylethynyl)indolizine-1-carbonitrile 
• 1268830-81-4 2-methyl-3-((methyl(p-tolyl)amino)methyl)indolizine-1-carbonitrile 
• 1268831-00-0 2-methyl-3-((methyl(phenyl)amino)methyl)indolizine-1-carbonitrile 
• 1200204-61-0 2-methyl-3-(1-phenylvinyl)indolizine-1-carbonitrile 
• 96206-94-9 (2-methylindolizin-1-yl)(phenyl)methanone 

Relevant articles and documents

Methylenecyclopropane Ring Formation/Opening Cascade for the Synthesis of Indolizines

A unique strategy toward the synthesis of polysubstituted indolizines has been developed. When 2-pyridinyl-2-(2′-bromoallyl)-1-carboxylates were treated with Cs2CO3, the starting material went through a methylenecyclopropane ring formation/opening cascade, and the corresponding indolizines were obtained in moderate to good yield as a single regioisomer.

Isocyanatophosphoric acid dichloride: A novel reagent for the introduction of a cyano group into the molecules of electron-rich heterocycles and enamines

A new synthetic method is developed which enables a direct one-step introduction of a cyano group into electron-rich heterocyclic systems of the indole, pyrrole, and indolizine series, and also to enamines using isocyanatophosphoryl dichloride.