32461-19-1

Upstream product

• 3592-47-0 Benzaldehyde-d 
• 98-86-2 acetophenone 
• 100-52-7 benzaldehyde 
• 42463-63-8 benzyl alcohol-α,α,hydroxy-d3 
• 65-85-0 benzoic acid 

Downstream Products

• 93698-11-4 3-deuterio-1,3-diphenyl-1-propanone 
• 93698-12-5 1,3-diphenylpropan-1-one-2,3-d₂ 
• 133533-73-0 5,7-diphenyl-7-deutero-4,5,6,7-tetrahydro-1,2,4-triazolo-<1,5-a>pyrimidine 

Relevant academic research and scientific papers

Stereoselective rearrangements with chiral hypervalent iodine reagents

I likes rearrangements: Hypervalent iodine compounds can be used as environmentally friendly, mild, and selective reagents for highly enantioselective rearrangements of alkenes. For the first time, rearrangements to α-arylated ketones can be performed enantioselectively using lactic acid-based iodine(III) reagents. Copyright

Transition-Metal-Free Self-Hydrogen-Transferring Allylic Isomerization

Phenanthroline and tert-butoxide have been established as powerful radical initiators in reactions such as the SRN1-type coupling reactions due to the cooperation of large heteroarenes and a special feature of tert-butoxide. The first phenanthroline-tert-butoxide-catalyzed transition-metal-free allylic isomerization is described. The resulting ketones are key intermediates for indenes. The control experiments rule out the base-promoted allylic anion pathway. The radical pathway is supported by experimental evidence that includes kinetic study, kinetic isotope effect, isotope-labeling experiments, trapping experiments, and EPR experiments.

Semiquantitative FMO Analysis of Substituent Effect on the Reaction of Permanganate Ion with Unsymmetrical Alkenes

The substituent effects on the reactions of permanganate ion with unsymmetrical alkenes are analyzed on the assumption of a concerted (3 + 2) cycloaddition model by using an equation obtained by approximation based on the FMO theory in which development and localization of the frontier molecular orbitals at the reaction sites with progress of the reaction are considered. The Hammett plots are successfully reproduced with the newly obtained rate data for the reactions of trans-chalcone and its derivatives and the data for methyl cinnamates, cinnamate ions, and alkyl vinyl ethers taken from the literature using FMO energies and orbital coefficients calculated by the PM3 method. It was indicated that a factor introduced to the basic equation in order to estimate the extent of localization of the molecular orbitals at the transition state is closely related to the position of the transition state along the reaction path.