325810-07-9

Basic information

• Product Name: (TrifluoroMethyl)tris(triphenylphosphine)copper(I)
• Synonyms: (TrifluoroMethyl)tris(triphenylphosphine)copper(I);(Trifluoromethyl)tris(triphenylphosphane)copper(I);Tris(triphenylphosphine)(trifluoroMethyl)copper(I), 99%
• CAS NO: 325810-07-9
• Molecular Formula: C₅₅H₄₅CuF₃P₃
• Molecular Weight: 919.4082926
• Mol File: 325810-07-9.mol

Chemical Properties

• Melting Point: 155 °C(dec.)
• Appearance: white/crystal
• Solubility: slightly sol. in Tetrahydrofuran
• Sensitive: air sensitive
• CAS DataBase Reference: (TrifluoroMethyl)tris(triphenylphosphine)copper(I)(CAS DataBase Reference)
• NIST Chemistry Reference: (TrifluoroMethyl)tris(triphenylphosphine)copper(I)(325810-07-9)
• EPA Substance Registry System: (TrifluoroMethyl)tris(triphenylphosphine)copper(I)(325810-07-9)

Safety Data

• Hazardous Substances Data: 325810-07-9(Hazardous Substances Data)

Usage

Reaction

Reagent used in the copper-mediated trifluoromethylation of propargylic halides and trifluoroacetates. Reagent used in a high-yielding simple preparation of trifluoromethylaromatics from iodides. Reagent used in the copper-mediated trifluoromethylation of allylic halides and trifluoroacetates.

Upstream product

• 75-46-7 trifluoromethan 
• 603-35-0 triphenylphosphine 
• 157371-59-0 Cu(OCH(CF₃)2)(P(C₆H₅)3)3 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 36820-10-7 Cu(OC₆H₅)(P(C₆H₅)3)3 

Downstream Products

• 145914-09-6 (4,4,4-trifluorobut-1-yn-1-yl)benzene 
• 1390640-13-7 (4,4,4-trifluorobuta-1,2-dien-1-yl)benzene 
• 1390640-16-0 1-fluoro-4-(4,4,4-trifluorobuta-1,2-dien-1-yl)benzene 
• 1390640-21-7 1-bromo-4-(4,4,4-trifluorobut-1-yn-1-yl)benzene 
• 1390640-17-1 1-(tert-butyl)-4-(4,4,4-trifluorobuta-1,2-dien-1-yl)benzene 
• 1390640-22-8 1-(tert-butyl)-4-(4,4,4-trifluorobut-1-yn-1-yl)benzene 
• 130716-13-1 (3,3,3-trifluoroprop-1-en-1-ylidene)cyclohexane 
• 1390640-18-2 1-methoxy-4-(4,4,4-trifluorobuta-1,2-dien-1-yl)benzene 
• 1390640-15-9 (5,5,5-trifluoropenta-2,3-dien-1-yl)benzene 
• 1446029-59-9 (E)-(6,6,6-trifluorohex-3-en-1-yl)benzene 
• 1446029-60-2 (E)-(4,4,4-trifluorobut-1-enyl)cyclohexane 
• 1446029-62-4 (E)-dimethyl(phenyl)(4,4,4-trifluorobut-1-en-1-yl)silane 
• 1415585-66-8 4-(prop-1-en-2-yl)-1-(2,2,2-trifluoroethyl)cyclohex-1-ene 
• 402-54-0 p-nitrobenzotrifluoride 

Relevant articles and documents

Copper-mediated trifluoromethylation-allylation of arynes

An unprecedented three-component copper-mediated vicinal trifluoromethylation-allylation of arynes is described. A wide range of structurally diverse trifluoromethylated allylarenes can be quickly assembled in one step. The application of the method has b

PROCESS TO OBTAIN A TRIFLUOROMETHYLATING COMPOSITION

Process to obtain a trifluoromethylating composition which comprises the reaction between a copper (I) source and a base in the presence of a solvent and between the resulting cuprating reagent with fluoroform.

Simple, stable, and easily accessible well-defined CuCF3 aromatic trifluoromethylating agents

Give me an F: Exceptionally easy to make in over 90 yield (see scheme) and air-stable in the solid state, [(Ph3P)3Cu(CF3)] is a remarkable example of a rarely encountered well-defined Cu(I) trifluoromethylating agent and a convenient starting material for the synthesis of other CuCF3 complexes, such as [(phen)Cu(PPh3)(CF 3)]. Copyright

C-Si bond cleavage of trihalomethyltrimethylsilane by alkoxo- and aryloxogold or -copper complexes

The C-Si bond cleavage of trihalomethyltrimethylsilane Me3SiCX3 (X = F, Cl) proceeds smoothly by alkoxo- and aryloxogold(I or III) or -copper(I) complexes Au(OR)L (OR = OCH(CF3)2, OPh), L =PCy3, PPhs