325959-20-4

Upstream product

• 69556-70-3 4-methoxy-5H-furan-2-one 
• 5788-17-0 methyl (2E)-3-methoxy-2-propenoate 
• 122-78-1 phenylacetaldehyde 
• 100-39-0 benzyl bromide 
• 325959-10-2 4-methoxy-5-phenylseleno-2(5H)-furanone 

Relevant academic research and scientific papers

Tetronic and tetramic acids

This invention relates to new tetronic and tetramic acid derivatives with beta-secretase inhibitory activity of formula I: wherein R1, R2, R3, R4, R5, R5′, R6 and R6′

Toward the synthesis of the antibiotic tetrodecamycin

We report here a short approach to a tricyclic substructure of tetrodecamycin exhibiting a unique ring skeleton utilising an acid catalysed ring closure as the key step. In addition an efficient three-step synthesis of 5-alkylidene 4-methoxy-2(5H)-furanones starting from 4-methoxy-2(5H)-furanone is described. (C) 2000 Elsevier Science Ltd.