32703-82-5 Usage
Uses
Used in Biological Research:
6-TERT-BUTYL-2,3-NAPHTHALENEDICARBONITRILE is used as a stain in biological research for its ability to bind and visualize specific cellular components and structures. Its staining properties make it a valuable tool for studying cell morphology, tracking cellular processes, and identifying specific cell types.
Used in Dyes and Metabolites:
In the field of dyes and metabolites, 6-TERT-BUTYL-2,3-NAPHTHALENEDICARBONITRILE is employed for its distinctive color and chemical properties. It can be used to develop new dyes with specific binding affinities or to create novel metabolites for various applications, such as in diagnostics or therapeutics.
Used in Analytical Chemistry:
6-TERT-BUTYL-2,3-NAPHTHALENEDICARBONITRILE can also be utilized in analytical chemistry as a reagent or a component in the development of new analytical methods. Its unique chemical structure allows for selective detection and quantification of specific compounds, enhancing the sensitivity and specificity of analytical techniques.
Used in Pharmaceutical Development:
Due to its chemical properties and potential biological activity, 6-TERT-BUTYL-2,3-NAPHTHALENEDICARBONITRILE may be explored for its potential use in pharmaceutical development. It could serve as a lead compound for the design of new drugs targeting specific biological pathways or as a component in drug delivery systems to improve the efficacy and safety of existing medications.
Used in Material Science:
In material science, 6-TERT-BUTYL-2,3-NAPHTHALENEDICARBONITRILE may find applications in the development of new materials with unique properties. Its chemical structure could be incorporated into polymers, coatings, or other materials to enhance their performance, durability, or functionality.
Biological Activity
BRD9876 is an inhibitor of the kinesin spindle protein Eg5. It arrests Eg5-mediated microtubule gliding, as well as inhibits Eg5 ATPase activity in the presence of microtubules, in cell-free assays. BRD9876 is cytotoxic to MM.1S stroma-independent multiple myeloma cells (IC50 = 2.2 μM). It induces cell cycle arrest at the G2/M phase in MM.1S cells when used at a concentration of 10 μM.
Check Digit Verification of cas no
The CAS Registry Mumber 32703-82-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,7,0 and 3 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 32703-82:
(7*3)+(6*2)+(5*7)+(4*0)+(3*3)+(2*8)+(1*2)=95
95 % 10 = 5
So 32703-82-5 is a valid CAS Registry Number.
InChI:InChI=1/C16H14N2/c1-16(2,3)15-5-4-11-6-13(9-17)14(10-18)7-12(11)8-15/h4-8H,1-3H3
32703-82-5Relevant academic research and scientific papers
Photophysical and photochemical properties and aggregation behavior of phthalocyanine and naphthalocyanine derivatives
de Souza, Thalita F. M.,Antonio, Felipe C. T.,Zanotto, Mateus,Homem-De-Mello, Paula,Ribeiro, Anderson O.
, p. 1199 - 1209 (2018/05/07)
The photophysical and photochemical properties of phthalocyanine and naphthalocyanine with similar structures were studied in solution and with density-functional theory (DFT) computational method. The extended π-conjugated system in naphthalocyanines causes a bathochromic shift in UV-Vis, emission and excitation bands, and promotes lesser generation of singlet oxygen in solution when compared to phthalocyanines. Time dependent DFT (TD-DFT) calculations point out the molecular orbitals involved in Q-band transition, corresponding to highest occupied molecular orbital (HOMO) to lowest unoccupied molecular orbital (LUMO) transition with a concentration of charge along x-axis, while the transition to LUMO+1 is in y-axis direction. The presence of tert-butyl substituents does not affect the molecular orbitals shape, but affect their energies. Aggregation studies in dimethyl sulfoxide (DMSO):water solutions showed that naphthalocyanines studied have more aggregation tendency than the phthalocyanines. DFT studies indicated that stacked-dimers are preferred to rotated-stacked conformation due the interaction between ZnII and nitrogen atom from different monomers.
Synthesis of soluble halogenated aryloxy substituted indium phthalocyanines
Plater,Jeremiah,Bourhill
, p. 91 - 96 (2007/10/03)
Phthalocyanines solubilised by either 8 or 16 aryloxy or haloaryloxy groups are described. A series of phthalocyanine derivatives were prepared containing indium. 1,2-Dinitriles and the corresponding diiminoisoindolines were used as precursors. A naphthalocyanine metallated with indium and solubilised with four tert-butyl groups is reported.
