327091-68-9Relevant academic research and scientific papers
Selective recyclization of 2-aroylmethyl-1H-benzimidazole hydrazones by condensation with dimethylformamide
Dzvinchuk,Vypirailenko,Lozinskii
, p. 1096 - 1101 (2007/10/03)
2-Aroylmethyl-1H-benzimidazole hydrazones are converted to 1-[pyrazol-3(5)-yl]benzimidazoles by refluxing in dimethylformamide in the presence of trifluoroacetic acid. The same products are obtained by refluxing 2-aroylmethyl-1H-benzimidazoles with hydrazine hydrochloride in dimethylformamide. Electron donor substituents in the para position of the aryl fragment of the starting compounds do not favor the reaction.
