327184-07-6Relevant academic research and scientific papers
A convenient approach to N-3 alkylation of 9-substituted guanines
Ostrowski, Tomasz,Zeidler, Joanna,Goelizski, Tomasz,Golankiewicz, Bozenna
, p. 565 - 567 (1999)
Aryl or tert-butyl substituent in the 6 position of 3,9-dihydro-3-[(2- hydroxy-ethoxy)methyl]-9-oxo-6-R-5H-imidazo[1,2-a]purine 1 directs the benzylation reaction partly into N-4 position to give 3. Cleavage of the third ring of 3 gives 3-benzylacycloguan
Substituent-directed aralkylation and alkylation reactions of the tricyclic analogues of acyclovir and guanosine
Ostrowski,Zeidler,Goslinski,Golankiewicz
, p. 1911 - 1929 (2007/10/03)
Aryl or tert-butyl substituent in the 6 position of 3,9-dihydro-3-[(2-hydroxyethoxy)methyl]-9-oxo-6-R-5H-imidazo[1,2-a]purine (6-R-TACV)11 partly directs aralkylation reactions into unusual positions: N-4 to give 3 and C-7 to give N-5,7-disubst
