A convenient approach to N-3 alkylation of 9-substituted guanines

Article abstract of DOI:10.1080/15257779908041495

Aryl or tert-butyl substituent in the 6 position of 3,9-dihydro-3-[(2- hydroxy-ethoxy)methyl]-9-oxo-6-R-5H-imidazo[1,2-a]purine 1 directs the benzylation reaction partly into N-4 position to give 3. Cleavage of the third ring of 3 gives 3-benzylacycloguan

Full text of DOI:10.1080/15257779908041495

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Nucleosides and Nucleotides
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A Convenient Approach to N-3 Alkylation
of 9-Substituted Guanines
Tomasz Ostrowski a , Joanna Zeidler a , Tomasz Goelizski a
Bozenna Golankiewicz a
&
a Institute of Bioorganic Chemistry, Polish Academy of Sciences ,
Noskowskiego 12/14, 61-704, Poznañ, Poland
Published online: 04 Oct 2006.
To cite this article: Tomasz Ostrowski , Joanna Zeidler , Tomasz Goelizski & Bozenna Golankiewicz
(1999) A Convenient Approach to N-3 Alkylation of 9-Substituted Guanines, Nucleosides and
Nucleotides, 18:4-5, 565-567, DOI: 10.1080/15257779908041495
To link to this article: http://dx.doi.org/10.1080/15257779908041495
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