327618-31-5

Basic information

• Product Name: 2-(TETRAHYDRO-FURAN-2-YL)-BENZOOXAZOLE
• Synonyms: 2-(TETRAHYDRO-FURAN-2-YL)-BENZOOXAZOLE;2-(tetrahydro-2-furanyl)Benzoxazole
• CAS NO: 327618-31-5
• Molecular Formula: C11H11NO2
• Molecular Weight: 189.213
• Mol File: 327618-31-5.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(TETRAHYDRO-FURAN-2-YL)-BENZOOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(TETRAHYDRO-FURAN-2-YL)-BENZOOXAZOLE(327618-31-5)
• EPA Substance Registry System: 2-(TETRAHYDRO-FURAN-2-YL)-BENZOOXAZOLE(327618-31-5)

Safety Data

• Hazardous Substances Data: 327618-31-5(Hazardous Substances Data)

Usage

Benzooxazole derivative

This indicates that the compound is derived from benzoxazole, a five-membered heterocyclic aromatic ring system.

Tetrahydrofuran group attached to the benzene ring

This describes the structure of the compound, indicating that a tetrahydrofuran group (a cyclic ether with four carbon atoms) is attached to the benzene ring of the benzoxazole.

Potential applications in drug discovery and pharmaceuticals

This suggests that the compound has potential for use in the development of new drugs and in the pharmaceutical industry.

Unique structure and potential biological activities

This indicates that the compound has a distinctive structure and may have biological effects that could be useful in drug development.

Should be handled with care and used in a controlled laboratory setting

This is a safety precaution, indicating that the compound may have potential hazards associated with its handling and use.

Upstream product

• 109-99-9 tetrahydrofuran 
• 91749-29-0 2-(methylsulfonyl)benzo[d]oxazole 
• 615-18-9 2-chloro-1,3-benzoxazole 
• 95-55-6 2-amino-phenol 
• 2843-27-8 N-(2-hydroxyphenyl)formamide 
• 1355021-17-8 2-isocyano-1-(2-tetrahydrofuranyloxy)benzene 
• 1355021-61-2 N-(2-(2-tetrahydrofuranyloxy)phenyl)formamide 
• 273-53-0 benzoxazole 

Relevant articles and documents

Aryl Ketone Mediated Photoinduced Radical Coupling for the Alkylation?-of Benzazoles Employing Saturated Heterocyclic Compounds?

An aryl ketone mediated synthesis of 2-alkylated benzazoles was achieved via radical coupling under photoirradiation starting from saturated heterocycles and 2-sulfonylated benzazoles, such as benzothiazoles, benzoxazole, and benzimidazole. Heterocyclic compounds, including a cyclic ether, azacycles, and tetrahydrothiophene, were applicable, and the benzazole unit was site-selectively installed at the carbon center proximal to the heteroatom. The present transformation takes place at ambient temperature under neutral reaction conditions without the aid of any metallic catalysts or reagents.

Heterogeneous Co-catalyzed direct 2-alkylation of azoles with ethers

The direct 2-alkylation of oxazoles and thiazoles with ethers through cross-dehydrogenative coupling reaction using Co-containing mesoporous zeolite ETS-10 as the heterogeneous catalyst is described. The basic Co-containing mesoporous zeolite ETS-10 catal

Light Induced C-C Coupling of 2-Chlorobenzazoles with Carbamates, Alcohols, and Ethers

A light induced, transition-metal-free C-C coupling reaction of 2-chlorobenzazoles with aliphatic carbamates, alcohols, and ethers is presented. Inexpensive reagents, namely sodium acetate, benzophenone, water, and acetonitrile, are employed in a simple reaction protocol using a cheap and widely available 25 W energy saving UV-A lamp at ambient temperature.