328396-52-7

Basic information

• Product Name: (2S,3R)-5-benzyl-2,3-O-isopropylidene-4-C-methylene-2-C-vinyl-D-erythro-pentitol
• Synonyms: (2S,3R)-5-benzyl-2,3-O-isopropylidene-4-C-methylene-2-C-vinyl-D-erythro-pentitol
• CAS NO: 328396-52-7
• Molecular Weight: 304.386
• Mol File: 328396-52-7.mol

Chemical Properties

• CAS DataBase Reference: (2S,3R)-5-benzyl-2,3-O-isopropylidene-4-C-methylene-2-C-vinyl-D-erythro-pentitol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R)-5-benzyl-2,3-O-isopropylidene-4-C-methylene-2-C-vinyl-D-erythro-pentitol(328396-52-7)
• EPA Substance Registry System: (2S,3R)-5-benzyl-2,3-O-isopropylidene-4-C-methylene-2-C-vinyl-D-erythro-pentitol(328396-52-7)

Safety Data

• Hazardous Substances Data: 328396-52-7(Hazardous Substances Data)

Upstream product

• 532-20-7 D-Ribose 
• 718604-58-1 2-Benzyloxy-1-[(4S,5S)-5-(1,2-dihydroxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-ethanone 
• 848862-75-9 1-O-tert-butyldiphenylsilyl-5-O-benzyl-2,3-O-isopropylidene-4-C-methylene-D-erythro-pentitol 
• 117174-48-8 1-O-tert-butyldiphenylsilyl-5-O-benzyl-2,3-O-isopropylidene-D-ribitol 
• 848862-73-7 1-O-tert-butyldiphenylsilyl-5-O-benzyl-2,3-O-isopropylidene-4-keto-D-erythro-pentitol 
• 130114-57-7 (2S,3R)-5-benzyl-2,3-O-isopropylidene-4-C-methylene-D-erytho-pentitol 
• 97204-83-6 (1R)-(+)-1-[(4R,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl]-2-(benzyloxy)ethan-1-ol 
• 67814-68-0 2,3-O-isopropylidene-D-ribofuranose 
• 1826-67-1 vinyl magnesium bromide 
• 495397-67-6 (4R,5R)-5-(1-Benzyloxymethyl-vinyl)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 718604-59-2 1-[(4S,5R)-5-(1-Benzyloxymethyl-vinyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-ethane-1,2-diol 
• 681853-94-1 (+)-1-[(4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl]-2-(benzyloxy)ethan-1-one 

Downstream Products

• 117307-62-7 (3aR,6aR)-6-Benzyloxymethyl-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-one 
• 328396-53-8 (4R,5S)-(-)-3-[(benzyloxy)methyl]-4,5-O-isopropylidene-2-cyclopenten-1-ol 

Relevant articles and documents

Preparative Synthesis of the Key Intermediate, (4R,5R)-3-Benzyloxymethyl-4,5-isopropylidenedioxycyclopent-2-enone for Carbocyclic Nucleosides

(4R,5R)-3-Benzyloxymethyl-4,5-isopropylidenedioxycyclopent-2-enone (1), a versatile intermediate for the synthesis of carbocyclic nucleosides was synthesized from D-ribose in 10 steps and 26 percent overall yield.

Synthesis using ring closure metathesis and effect on nucleoside transport of a (N)-methanocarba S-(4-nitrobenzyl)thioinosine derivative

(Matrix presented) A new synthetic route to ring-constrained (N)-methanocarba nucleosides and nucleotides is presented. Ring closure of a diene intermediate usina Grubbs catalyst provides a new avenue for the preparation of the cyclopentenone derivative 6