328396-53-8Relevant articles and documents
Preparative Synthesis of the Key Intermediate, (4R,5R)-3-Benzyloxymethyl-4,5-isopropylidenedioxycyclopent-2-enone for Carbocyclic Nucleosides
Moon, Hyung Ryong,Choi, Won Jun,Kim, Hea Ok,Jeong, Lak Shin
, p. 506 - 507 (2007/10/03)
(4R,5R)-3-Benzyloxymethyl-4,5-isopropylidenedioxycyclopent-2-enone (1), a versatile intermediate for the synthesis of carbocyclic nucleosides was synthesized from D-ribose in 10 steps and 26 percent overall yield.
Synthesis using ring closure metathesis and effect on nucleoside transport of a (N)-methanocarba S-(4-nitrobenzyl)thioinosine derivative
Lee, Kyeong,Cass, Carol,Jacobson, Kenneth A.
, p. 597 - 599 (2007/10/03)
(Matrix presented) A new synthetic route to ring-constrained (N)-methanocarba nucleosides and nucleotides is presented. Ring closure of a diene intermediate usina Grubbs catalyst provides a new avenue for the preparation of the cyclopentenone derivative 6