848862-73-7Relevant articles and documents
Synthetic studies toward the preparation of (4R,5R)-(-)-3-[(benzyloxy) methyl]-4,5-O-isopropylidene-cyclopenten-2-one: An important synthetic intermediate for carbanucleosides
Elhalem, Eleonora,Comin, Maria J.,Leitofuter, Julieta,Garcia-Linares, Guadalupe,Rodriguez, Juan B.
, p. 425 - 431 (2007/10/03)
The carbocyclic compound (4R,5R)-(-)-3-[(benzyloxy)methyl]-4,5-O- isopropylidene-2-cyclopentenone 1 is an important synthetic intermediate to access a variety of carbanucleosides. Herein, synthetic studies that lead to this valuable compound employing ine
Synthesis using ring closure metathesis and effect on nucleoside transport of a (N)-methanocarba S-(4-nitrobenzyl)thioinosine derivative
Lee, Kyeong,Cass, Carol,Jacobson, Kenneth A.
, p. 597 - 599 (2007/10/03)
(Matrix presented) A new synthetic route to ring-constrained (N)-methanocarba nucleosides and nucleotides is presented. Ring closure of a diene intermediate usina Grubbs catalyst provides a new avenue for the preparation of the cyclopentenone derivative 6