32884-73-4

Basic information

• Product Name: 1H-Indole, 3-[(4-chlorophenyl)thio]-
• CAS NO: 32884-73-4
• Molecular Formula: C14H10ClNS
• Molecular Weight: 259.759
• Mol File: 32884-73-4.mol
• Article Data: 41

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 3-[(4-chlorophenyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 3-[(4-chlorophenyl)thio]-(32884-73-4)
• EPA Substance Registry System: 1H-Indole, 3-[(4-chlorophenyl)thio]-(32884-73-4)

Safety Data

• Hazardous Substances Data: 32884-73-4(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 637-87-6 1-Chloro-4-iodobenzene 
• 1466-88-2 2-nitrocinnamic aldehyde 
• 106-54-7 p-Chlorothiophenol 
• 496-15-1 1-indoline 
• 13165-81-6 ethyl p-chlorobenzenesulphinate 
• 106-46-7 para-dichlorobenzene 
• 17356-08-0 thiourea 
• 64605-23-8 2'-amino-2-chloroacetophenone 
• 50695-53-9 N-(p-chlorobenzenesulfonyl)hydroxylamine 
• 30384-54-4 sodium S-(4-chlorophenyl) thiosulfate 
• 100-03-8 4-chlorobenzenesulfinic acid 

Downstream Products

• 139493-28-0 2-<(4-chlorophenyl)thio>indole 

Relevant articles and documents

Flavin/I2-Catalyzed Aerobic Oxidative C–H Sulfenylation of Aryl-Fused Cyclic Amines

We report an aerobic oxidative C–H sulfenylation of aryl-fused cyclic amines with various thiols catalyzed by flavin/I2 for the first time. While flavin I catalyzed the C–H sulfenylation of indolines to afford 3-sulfenylindoles, flavin II enabl

Cuprous complex, preparation method thereof and application of cuprous complex in synthesis of 3-indolyl thioether

The invention relates to a cuprous complex, a preparation method thereof and an application of the cuprous complex in synthesis of 3-indolyl thioether. The structural formula of the cuprous complex isshown in the specification, Ar is aryl containing a benzene ring or heterocyclic aryl, and ''.'' is a boron hydrogen bond; the preparation method comprises the following steps: 1) dissolving ortho-carborane diformaldehyde and arylamine in an organic solvent, reacting at 60-100 DEG C, and cooling to room temperature after the reaction is finished; and 2) adding CuI, reacting at room temperature for 3-6 hours, and separating to obtain the cuprous complex. Compared with the prior art, the cuprous complex containing the ortho-position carborane Schiff base ligand can efficiently catalyze the coupling reaction of synthesizing a 3-indolyl thioether compound from indole and thiophenol, the method has the advantages of high selectivity, low catalyst dosage, mild reaction conditions, open reaction(taking air as an oxidant), high reaction rate, high yield, wide substrate range and the like and shows a wide industrial application prospect.

NH4I/1,10-phenanthroline catalyzed direct sulfenylation of N-heteroarenes with ethyl arylsulfinates

An efficient synthesis of N-heterocyclic aryl sulfides via NH4I/1,10-phenanthroline-catalyzed direct sulfenylation reactions was reported. In this reaction, heteroarenes such as indoles, and pyrroles serve as nucleophiles by installing a arylthio group at the C3 and C2 position of heterocycles, respectively. With readily accessible and free of unpleasant odor ethyl arylsulfinates as sulfur reagents, the metal-free-catalyzed direct sulfenylation of N-heteroarenes has been developed. 3-Arylthio-indoles and 2-arylthio-pyrroles derivatives were obtained in moderate to excellent yields, even on gram scale. The reaction was general for a broad scope of substrates and demonstrated good tolerance to a variety of functional groups.