329328-48-5Relevant academic research and scientific papers
New rubrolide analogues as inhibitors of photosynthesis light reactions
Varej?o, Jodieh O.S.,Barbosa, Luiz C.A.,Ramos, Gabriela álvarez,Varej?o, Eduardo V.V.,King-Díaz, Beatriz,Lotina-Hennsen, Blas
, p. 11 - 18 (2015)
Natural products called rubrolides have been investigated as a model for the development of new herbicides that act on the photosynthesis apparatus. This study comprises a comprehensive analysis of the photosynthesis inhibitory ability of 27 new structura
Palladium-catalyzed hydrodehalogenation of butenolides: An efficient and sustainable access to β-arylbutenolides
Karak, Milandip,Barbosa, Luiz C.A.,Maltha, Celia R.A.,Silva, Thiago M.,Boukouvalas, John
supporting information, p. 2830 - 2834 (2017/06/27)
Several α-unsubstituted β-arylbutenolides have been prepared in 69–92% yield by reductive dehalogenation of α-halo-β-arylbutenolides. The latter were assembled in a single-step from α,β-dihalobutenolides, which are accessible on a large-scale from biomass-derived furfural. Our dehalogenation protocol is illustrated by a new synthesis of the marine antibiotics rubrolide E and F, and 3″-bromorubrolide F.
Selective synthesis of (Z)-4-aryl-5-[1-(aryl)methylidene]-3-bromo-2(5H)-furanones
Bellina, Fabio,Anselmi, Chiara,Viel, Stéphane,Mannina, Luisa,Rossi, Renzo
, p. 9997 - 10007 (2007/10/03)
4-Aryl-3-bromo-2(5H)-furanones have been selectively synthesized in satisfactory yields by treatment of easily available 3,4-dibromo-2(5H)-furanone either with arylboronic acids in the presence of Ag2O and a catalytic amount of PdCl2(MeCN)2 or with aryl(trialkyl)stannanes in the presence of a catalyst precursor consisting of AsPh3 and a Pd(II) or a Pd(0) compound. These monobromo derivatives have been then used as precursors to a variety of (Z)-4-aryl-5-[1-(aryl)methylidene]-3-bromo-2(5H)-furanones including the compound with the structure corresponding to that reported for naturally occurring rubrolide N. The structure and stereochemistry of these synthetic compounds have been unambiguously established by NMR techniques.
Selective synthesis of unsymmetrical 3,4-disubstituted and 4-substituted 2(5H)-furanones
Rossi,Bellina,Raugei
, p. 1749 - 1752 (2007/10/03)
Easily available 3,4-dibromo-2(5H)-furanone undergoes regioselective palladium-catalyzed reaction with aryl(trialkyl)stannanes to give the corresponding 4-aryl-3-bromo-2(5H)-furanones in satisfactory yields. These monobromo derivatives have proven to be useful precursors to unsymmetrical 3,4-diaryl-2(5H)-furanones, 4-aryl-3-methyl-2(5H)-furanones and 4-aryl-2(5H)-furanones.
