32978-41-9Relevant academic research and scientific papers
Method for synthesizing acetylenic acid by using terminal alkyne and carbon dioxide
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Paragraph 0178-0186, (2021/07/24)
The invention belongs to the field of organic synthesis, and particularly relates to a method for synthesizing acetylenic acid by using terminal alkyne and carbon dioxide. The method comprises the experimental steps that alkyne, alkali and a solvent are added into a reaction tube, the alkyne serves as a raw material, the alkali and the solvent provide a strong alkaline environment, CO2 is introduced into a reaction container to form a carbon dioxide atmosphere, heating and stirring reaction are carried out, after the reaction is finished, cooling is carried out to the room temperature, extraction and liquid separation are carried out, a water layer is acidified, then separation and purification are further carried out, and the acetylenic acid compound is obtained. The method is carried out under the conditions of low temperature and normal pressure, does not need to add a metal catalyst, is single in product and convenient to separate, good in substrate applicability and safe and simple to operate, and has potential industrial application prospects and good economic benefits.
Carboxylation of terminal alkynes with CO2 using novel silver N-heterocyclic carbene complexes
Li, Shanshan,Sun, Jing,Zhang, Zhizhi,Xie, Ruixia,Fang, Xiangchen,Zhou, Mingdong
, p. 10577 - 10584 (2016/07/07)
Four novel N-heterocyclic carbene (NHC) silver complexes, I-IV, have been synthesized and characterized. The single X-ray crystal diffraction data indicate a dinuclear solid-state structure for I and III and a mononuclear structure for II and IV. These complexes have been successfully used as efficient catalysts for the C-H activating carboxylation of terminal alkynes with CO2. A wide range of substrates with various functional groups afforded the corresponding aryl or alkyl substituted propiolic acids in good yields under mild conditions. Moreover, the role of bases and the reaction mechanism is thoroughly discussed.
Carbon dioxide capture and use: Organic synthesis using carbon dioxide from exhaust gas
Kim, Seung Hyo,Kim, Kwang Hee,Hong, Soon Hyeok
supporting information, p. 771 - 774 (2014/01/23)
A carbon capture and use (CCU) strategy was applied to organic synthesis. Carbon dioxide (CO2) captured directly from exhaust gas was used for organic transformations as efficiently as hyper-pure CO2 gas from a commercial source, even for highly air- and moisture-sensitive reactions. The CO2 capturing aqueous ethanolamine solution could be recycled continuously without any diminished reaction efficiency. Exhaust gas is good enough! Carbon dioxide captured directly from exhaust gas was used for organic syntheses (see picture) as efficiently as hyper-pure CO2 gas from a commercial source, even for highly air- and moisture-sensitive reactions. The CO2 capturing aqueous ethanolamine solution could be recycled continuously without any diminished reaction efficiency. Copyright
Ligand-free Ag(I)-catalyzed carboxylation of terminal alkynes with CO 2
Zhang, Xiao,Zhang, Wen-Zhen,Ren, Xiang,Zhang, Lin-Lin,Lu, Xiao-Bing
supporting information; experimental part, p. 2402 - 2405 (2011/06/25)
Chemical equations presented. A convenient approach to selectively prepare a wide range of functionalized propiolic acids was developed by AgI-catalyzed carboxylation of terminal alkynes using carbon dioxide as carboxylative agent under ligand-free conditions.
