3307-32-2Relevant academic research and scientific papers
NANOMATERIALS
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Paragraph 0460-0462, (2021/07/17)
Lipid nanoparticle compositions for delivery of nucleic acids are described. In various embodiments the lipid nanoparticle contains an ionizable lipid of the Formula (I). Methods of using such lipid nanoparticle compositions to achieve targeted delivery of therapeutic cargo without the need for a targeting ligand are also provided.
Organic Synthesis Utilizing Beckmann Fragmentation: New Carbon-Carbon Bond Formation by the Reaction of α-Alkoxycycloalkanone Oxime Acetates with Organoaluminium Reagents
Fujioka, Hiromichi,Yamanaka, Takeshi,Takuma, Kazuhiro,Miyazaki, Makoto,Kita, Yasuyuki
, p. 533 - 534 (2007/10/02)
The reaction of α-alkoxycycloalkanone oxime acetates 1 with organoaluminium reagents caused Beckmann fragmentation and subsequent carbon-carbon bond formation to give various types of ω-cyano-α-alkyl (or alkynyl)ethers 2 in high yields.
Beckmann fragmentation and successive carbon-carbon bond formation of α-alkoxycycloalkanone oximes catalyzed by trimethylsilyl trifluoromethanesulfonate
Fujioka,Miyazaki,Yamanaka,Yamamoto,Kita
, p. 5951 - 5954 (2007/10/02)
Title reaction occurred in the presence of silicon-containing carbon nucleophiles and various types of functionalized ω-nitrile compounds were obtained from the oximes in one-pot operation.
