331442-12-7

Basic information

• Product Name: BOC-HYP-OH
• Synonyms: RARECHEM EM WB 0136;N-BOC-TRANS-4-HYDROXY-L-PROLINE;N-BOC-L-TRANS-4-HYDROXYPROLINE;N-BOC-L-4-HYDROXYPROLINE;N-BOC-4-HYDROXY-L-PROLINE;N-ALPHA-T-BUTOXYCARBONYL-TRANS-4-HYDROXY-L-PROLINE;N-ALPHA-TERT-BUTYLOXYCARBONYL-L-4-HYDROXYPROLINE;N-ALPHA-T-BOC-L-TRANS-4-HYDROXYPROLINE
• CAS NO: 331442-12-7
• Molecular Formula: C₁₀H₁₇NO₅
• Molecular Weight: 231.25
• Mol File: 331442-12-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 123-127 °C(lit.)
• Boiling Point: 390.9 °C at 760 mmHg
• Flash Point: 190.2 °C
• Appearance: /
• Density: 1.312 g/cm³
• Vapor Pressure: 9.99E-08mmHg at 25°C
• Refractive Index: 1.531
• Storage Temp.: −20°C
• PKA: 3.80±0.40(Predicted)
• CAS DataBase Reference: BOC-HYP-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-HYP-OH(331442-12-7)
• EPA Substance Registry System: BOC-HYP-OH(331442-12-7)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 331442-12-7(Hazardous Substances Data)

Usage

General Description

BOC-HYP-OH, also known as Nα-BOC-L-hydroxyproline, is a synthetic derivative of the amino acid hydroxyproline. It is commonly used in peptide synthesis as a protective group for hydroxyproline residues, allowing for selective modifications of peptides. BOC-HYP-OH is often employed in the production of collagen-based biomaterials, as well as in the development of pharmaceuticals and other bioactive compounds. This chemical plays a crucial role in the field of organic chemistry and biochemistry, facilitating the creation of complex peptides and molecules with specific properties and functions.

InChI:InChI=1/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)

Upstream product

• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 51-35-4 4R-4-hydroxyproline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 51-35-4 4-hydroxyproline 
• 144-55-8 sodium hydrogencarbonate 

Downstream Products

• 1001383-50-1 trans-4-hydroxy-L-proline methyl ester 
• 84520-67-2 (2S,4R)-4-(methylsulfonyloxy)pyrrolidine-1,2-dicarboxylic acid 1-tert-butylester-2-methylester 
• 88501-00-2 (2S,4R)-4-hydroxyproline benzyl ester p-toluenesulfonate 
• 426844-50-0 (S)-2-carbamoyl-4,4-difluoropyrrolidine-1-carboxylic acid tert-butyl ester 
• 84348-37-8 N-tert-butoxycarbonyl-4-oxo-L-proline 
• 103057-44-9 N-(tert-butoxycarbonyl)-3-hydroxypyrrolidine 
• 128120-92-3 (S)-4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-(2-oxo-2-phenyl-ethyl) ester 

Relevant articles and documents

Methods for modulating phototoxicity

The invention relates to methods for modulating photodamage via the use of collagen derived molecules which either enhance or inhibit damage caused by ultraviolet light.

SUBSTITUTED 4-PHENOXY OR 4-PHENYLTHIO PROLINES

This invention is directed to substituted 4-phenoxy and 4-phenylthio prolines of the formula STR1 which possess useful hypotensive activity.