33149-48-3

Basic information

• Product Name: 2-methyl[1]benzofuro[3,2-d]pyrimidin-4(1H)-one
• Synonyms: Benzofuro[3,2-d]pyrimidin-4(3H)-one, 2-methyl-
• CAS NO: 33149-48-3
• Molecular Formula: C₁₁H₈N₂O₂
• Molecular Weight: 200.1934
• Mol File: 33149-48-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 373.3°C at 760 mmHg
• Flash Point: 179.6°C
• Density: 1.46g/cm³
• Vapor Pressure: 9.06E-06mmHg at 25°C
• Refractive Index: 1.717
• CAS DataBase Reference: 2-methyl[1]benzofuro[3,2-d]pyrimidin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl[1]benzofuro[3,2-d]pyrimidin-4(1H)-one(33149-48-3)
• EPA Substance Registry System: 2-methyl[1]benzofuro[3,2-d]pyrimidin-4(1H)-one(33149-48-3)

Safety Data

• Hazardous Substances Data: 33149-48-3(Hazardous Substances Data)

Upstream product

• 75746-20-2 3-amino-3,4-dihydro-2-methyl-4-oxobenzofuro<3,2-d>pyrimidine 
• 54802-13-0 3-acetylamino-benzofuran-2-carboxylic acid 
• 39786-35-1 ethyl 3-aminobenzofuran-2-carboxylate 
• 80551-19-5 3-chloroacetylamino-2-benzofurancarboxamide 
• 80550-76-1 2-chloromethyl-3,4-dihydro-4-oxobenzofuro<3,2-d>pyrimidine 
• 54802-10-7 3-aminobenzofuran-2-carboxamide 
• 39786-38-4 ethyl 3-acetylamino-2-benzofurancarboxylate 
• 57753-09-0 3-bromo-4-methoxy-2H-chromen-2-one 
• 76853-89-9 3-chloro-4-methoxy-2H-chromen-2-one 
• 20280-81-3 4-methoxycoumarin 
• 76853-97-9 bromo-3 methylcarbonimidoylamino-4 coumarine 
• 76853-93-5 chloro-3 methylcarbonimidoylamino-4 coumarine 
• 80551-01-5 2-cyanomethyl-3,4-dihydro-4-oxobenzofuro<3,2-d>pyrimidine 
• 68217-77-6 3-acetylamino-2-benzofurancarboxamide 

Downstream Products

• 39786-40-8 4-chloro-2-methylbenzofuro<3,2-d>pyrimidine 
• 68217-94-7 2-Methyl-3,4-dihydro-4-thio-benzofuro<3,2-d>pyrimidin 
• 68217-88-9 4-(2-chloro-phenylsulfanyl)-2-methyl-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-82-3 4-(2-chloro-phenoxy)-2-methyl-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-83-4 4-(4-chloro-phenoxy)-2-methyl-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-93-6 cyclohexyl-(2-methyl-benzo[4,5]furo[3,2-d]pyrimidin-4-yl)-amine 
• 68217-86-7 4-benzylsulfanyl-2-methyl-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-87-8 2-methyl-4-phenylsulfanyl-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-81-2 2-methyl-4-phenoxy-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-90-3 (2-methyl-benzo[4,5]furo[3,2-d]pyrimidin-4-yl)-phenyl-amine 

Relevant articles and documents

THIENO[2,3-D)PYRIMIDINES AND BENZOFURO(3,2-D)PYRIMIDINES AS ANTIMICROBIAL AGENTS

The present disclosure provides compounds, methods, and compositions which may be used to treat tuberculosis. In some embodiments, these compounds and compositions have a bactericidal property against Mycobacterium tuberculosis (Mtb). Methods of employing such agents are also provided.

Studies in Benzofurans : Part VIII-Synthesis of Some 3-N-aryl-, 3-N-Alkyl- and 3-Amino-3,4-dihydro-4-oxobenzofuropyrimidines

Ethyl 3-amino-2-benzofuran-carboxylate (I) on condensation with ethyl orthoformate and various aromatic amines affords 3-N-aryl-3,4-dihydro-4-oxobenzofuropyrimidines (II).Analogous 3-alkyl and 3-amino compounds have been prepared by the reaction of ethyl 3-(ethoxymethylene)amino-2-benzofurancarboxylate (III) with aliphatic amines and hydrazine hydrate respectively.