33149-48-3

Upstream product

• 13099-95-1 ethyl 2,3-dihydro-3-oxo-benzofuran-2-carboxylate 
• 124-42-5 acetamidine hydrochloride 
• 57805-83-1 2-methyl-benzo[4,5]furo[3,2-d][1,3]oxazin-4-one 
• 68217-77-6 3-acetylamino-2-benzofurancarboxamide 
• 80551-01-5 2-cyanomethyl-3,4-dihydro-4-oxobenzofuro<3,2-d>pyrimidine 
• 75746-20-2 3-amino-3,4-dihydro-2-methyl-4-oxobenzofuro<3,2-d>pyrimidine 
• 76853-93-5 chloro-3 methylcarbonimidoylamino-4 coumarine 
• 76853-97-9 bromo-3 methylcarbonimidoylamino-4 coumarine 
• 39786-35-1 ethyl 3-aminobenzofuran-2-carboxylate 
• 54802-13-0 3-acetylamino-benzofuran-2-carboxylic acid 
• 80551-19-5 3-chloroacetylamino-2-benzofurancarboxamide 
• 80550-76-1 2-chloromethyl-3,4-dihydro-4-oxobenzofuro<3,2-d>pyrimidine 
• 54802-10-7 3-aminobenzofuran-2-carboxamide 
• 39786-38-4 ethyl 3-acetylamino-2-benzofurancarboxylate 

Downstream Products

• 39786-40-8 4-chloro-2-methylbenzofuro<3,2-d>pyrimidine 
• 68217-94-7 2-Methyl-3,4-dihydro-4-thio-benzofuro<3,2-d>pyrimidin 
• 68217-88-9 4-(2-chloro-phenylsulfanyl)-2-methyl-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-82-3 4-(2-chloro-phenoxy)-2-methyl-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-83-4 4-(4-chloro-phenoxy)-2-methyl-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-93-6 cyclohexyl-(2-methyl-benzo[4,5]furo[3,2-d]pyrimidin-4-yl)-amine 
• 68217-86-7 4-benzylsulfanyl-2-methyl-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-87-8 2-methyl-4-phenylsulfanyl-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-81-2 2-methyl-4-phenoxy-benzo[4,5]furo[3,2-d]pyrimidine 
• 68217-90-3 (2-methyl-benzo[4,5]furo[3,2-d]pyrimidin-4-yl)-phenyl-amine 

Relevant academic research and scientific papers

THIENO[2,3-D)PYRIMIDINES AND BENZOFURO(3,2-D)PYRIMIDINES AS ANTIMICROBIAL AGENTS

The present disclosure provides compounds, methods, and compositions which may be used to treat tuberculosis. In some embodiments, these compounds and compositions have a bactericidal property against Mycobacterium tuberculosis (Mtb). Methods of employing such agents are also provided.

Studies in Benzofurans: Part XII - Synthesis and Reactions of 2-Chloromethyl-3,4-dihydro-4-oxobenzofuropyrimidine

Syntheses of 2-chloromethyl-3,4-dihydro-4-oxobenzofuropyrimidine (II) and 2-hydroxymethyl-3,4-dihydro-4-oxobenzofuropyrimidine (III) and their conversion into 2-chloromethyl-4-chlorobenzofuropyrimidine (IV) are reported.Various nucleophilic displacement reactions of II and IV have been investigated.

Studies in Benzofurans : Part VIII-Synthesis of Some 3-N-aryl-, 3-N-Alkyl- and 3-Amino-3,4-dihydro-4-oxobenzofuropyrimidines

Ethyl 3-amino-2-benzofuran-carboxylate (I) on condensation with ethyl orthoformate and various aromatic amines affords 3-N-aryl-3,4-dihydro-4-oxobenzofuropyrimidines (II).Analogous 3-alkyl and 3-amino compounds have been prepared by the reaction of ethyl 3-(ethoxymethylene)amino-2-benzofurancarboxylate (III) with aliphatic amines and hydrazine hydrate respectively.

Sur les possibilites de formation de pyrimidines a partir d'halogeno-3 methoxy-4 coumarines

3-chloro and 3-bromo-4-methoxycoumarins are tranformed by guanidine into 2-amino-5-halo-6-(2-hydroxyphenyl)-4-oxo-3,4-dihydropyrimidines.However, by treatment with benzamidine and acetamidine they lead, not only to the expected pyrimidines, but also to th