3316-54-9

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 7-hydroxy-5,8-dimethoxy-2-phenyl-
• CAS NO: 3316-54-9
• Molecular Formula: C17H14O5
• Molecular Weight: 298.295
• Mol File: 3316-54-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 7-hydroxy-5,8-dimethoxy-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 7-hydroxy-5,8-dimethoxy-2-phenyl-(3316-54-9)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 7-hydroxy-5,8-dimethoxy-2-phenyl-(3316-54-9)

Safety Data

• Hazardous Substances Data: 3316-54-9(Hazardous Substances Data)

Upstream product

• 480-40-0 5,7-dihydroxy-2-phenyl-chromen-4-one 
• 123549-16-6 7-hydroxy-5,8-dimethoxyflavone 7-O-β-D-glucuronopyranoside 
• 7499-99-2 1-(2,4-dihydroxy-3,6-dimethoxy)phenylethanone 
• 93-97-0 benzoic acid anhydride 
• 532-32-1 sodium benzoate 
• 742076-91-1 7-benzyloxy-5,8-dimethoxy-2-phenyl-chromen-4-one 
• 857564-84-2 1-(2,4-bis-benzoyloxy-3,6-dimethoxy-phenyl)-ethanone 
• 54299-50-2 2',4'-dihydroxy-3',6'-dimethoxychalcone 
• 102-92-1 cinnamoyl chloride 
• 20032-42-2 2,5-dimethoxyresorcinol 
• 6274-74-4 2,6-dibenzyloxy-1,4-dimethoxybenzene 
• 42528-81-4 2,6-bis-benzyloxy-benzene-1,4-diol 
• 6625-45-2 2,6-bis-benzyloxy-[1,4]benzoquinone 
• 87-66-1 2-hydroxyresorcinol 

Downstream Products

• 94879-97-7 5,7,8-triacetoxy-2-phenyl-chromen-4-one 
• 84757-43-7 5,7-dihydroxy-6-formyl-8-methoxyflavone 
• 23050-38-6 5,7,8-trimethoxy-2-phenyl-chromen-4-one 
• 3570-62-5 5-hydroxy-7,8-dimethoxyflavone 
• 491-67-8 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one 
• 4443-09-8 norwogonin 

Relevant articles and documents

Synthesis, evaluation and quantitative structure–activity relationship (QSAR) analysis of Wogonin derivatives as cytotoxic agents

A novel series of 49 wogonin derivatives were synthesized by introducing group at 7-, 8- or B ring of wogonin. The cytotoxic activities against HepG2, A549 and BCG-823 cancer cell lines were also investigated in vitro. Several of them showed obvious cytotoxic activities and compound 3h possessed the highest potency against HepG2, A549, and BCG-823 with IC50 values of 1.07 μM, 1.74 μM and 0.98 μM, respectively. A quantitative structure-activity relationship (QSAR) study of these synthetic derivatives as well as wogonin indicated that high solubility and low octanol/water partition coefficient are favorable, and excessive electrostatic properties and refractivity are unfavorable for the cytotoxic activities of these wogonin derivatives. These findings and results provide a base for further investigations.

Studies on the constituents of Scutellaria species. XIII. On the flavonoid constituents of the root of Scutellaria rivularis wall

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