33192-10-8

Basic information

• Product Name: 2-methyl-4-thiocyanato-aniline
• Synonyms: 2-methyl-4-thiocyanato-aniline
• CAS NO: 33192-10-8
• Molecular Formula: C₈H₈N₂S
• Molecular Weight: 164.23
• Mol File: 33192-10-8.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 314.2°Cat760mmHg
• Flash Point: 143.9°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 0.000472mmHg at 25°C
• Refractive Index: 1.629
• CAS DataBase Reference: 2-methyl-4-thiocyanato-aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-4-thiocyanato-aniline(33192-10-8)
• EPA Substance Registry System: 2-methyl-4-thiocyanato-aniline(33192-10-8)

Safety Data

• Hazardous Substances Data: 33192-10-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H8N2S/c1-6-4-7(11-5-9)2-3-8(6)10/h2-4H,10H2,1H3

Upstream product

• 7647-01-0 hydrogenchloride 
• 1147550-11-5 ammonium thiocyanate 
• 95-53-4 o-toluidine 
• 7677-24-9 trimethylsilyl cyanide 
• 333-20-0 potassium thioacyanate 

Downstream Products

• 23530-68-9 2-chloro-6-methyl-4-thiocyanato-aniline 
• 106378-70-5 (2-methyl-4-methylsulfanyl-phenyl)-phenyl-diazene 
• 106038-77-1 3-methyl-4-phenylazo-phenyl thiocyanate 
• 88070-26-2 acetic acid-(2-methyl-4-thiocyanato-anilide) 
• 88070-23-9 bis-(4-amino-3-methyl-phenyl)-disulfide 
• 18954-02-4 (2-methyl-4-thiocyanato-phenyl)-urea 
• 88070-24-0 bis-(4-acetylamino-3-methyl-phenyl)-disulfide 

Relevant articles and documents

Isoquinolinium-N-sulfonic acid thiocyanate/H2O2 as efficient reagent for thiocyanation of N-bearing (hetero)aromatic compounds

In the present study, isoquinoline sulfonic acid thiocyanate (isoquinoline-SO3H)SCN and isoquinoline sulfonic acid chloride (isoquinoline-SO3H)Cl as a novel and heterogeneous catalyst were designed and synthesized by a simple and ine

Visible-light-enabled regioselective aerobic oxidative C(sp2)-H thiocyanation of aromatic compounds by Eosin-Y photocatalyst

Herein, visible-light-enabled regioselective aerobic oxidative C(sp2)-H thiocyanation of aromatic compounds has been developed by employing eosin-Y as effective photocatalyst and oxygen as the green terminal oxidant. This process featured green, efficient and operationally simple. Furthermore, the practicality and utility of this protocol was demonstrated by the gram scale synthesis. Mechanistic studies suggested that this reaction was realized via a photoredox radical pathway.

Visible light thiocyanation of: N -bearing aromatic and heteroaromatic compounds using Ag/TiO2 nanotube photocatalyst

In this study, Ag/TiO2 nanotubes (Ag/TNT) were synthesized via simple hydrothermal process, and this photocatalyst was successfully exploited in thiocyanation reactions at room temperature under visible light irradiation. Four classes of important heterocyclic compounds including indole, aniline, pyrrole and 2-amino thiazole derivatives via Ag/TNT treated with ammonium thiocyanate formed the corresponding thiocyano compounds in moderate to excellent yields. Plasmonic property and catalytic performance of Ag nanoparticles (which mainly deposited on the surface of TNT) in absorbing species containing sulfur atoms were key components for the reactions to proceed. This potent, simple and versatile protocol reported for the first time afforded thiocyanation reactions of aniline, pyrrole and 2-amino thiazole derivatives under visible light. The reactions proceeded through a radical pathway by applying air molecular oxygen as a low-cost and environmentally friendly terminal oxidant.