3328-28-7Relevant academic research and scientific papers
Novel synthesis of 3-carboxamidolactam derivatives via palladium-catalysed aminocarbonylation
Kollár, László,Takács, Attila
, p. 6116 - 6128 (2018/09/12)
Aminocarbonylation of alkenyl and (hetero)aryl iodides using medium-sized 3-aminolactams as N-nucleophiles was carried out in the presence of in situ palladium(0) catalysts. While the iodoalkenes were converted to the corresponding carboxamide under mild
ANTI-INFLAMMATORY AGENTS
-
Page/Page column 22-23, (2012/01/05)
Disclosed herein are methods of preventing or treating inflammatory diseases using 3 - aminolactam compounds, each with aromatic "tail groups". Compounds as defined by formulae (I) and (I'), and the medical uses of the compounds, are described herein.
Aminothiazole derivative. I. A convenient synthesis of monocyclic and condensed 5-aminothiazole derivatives
Uchikawa,Fukatsu,Aono
, p. 877 - 887 (2007/10/02)
Treatment of diamides derived from α-amino acids with phosphorus pentasulfide or Lawesson's reagent was shown to provide a convenient method to prepare 5-aminothiazoles. By this method, in addition to monocyclic 5-aminothiazoles 19, novel bicyclic 5-aminothiazole derivatives such as 4,5,6,7-tetrahydrothiazolo[5,4-b]pyridines II, 5,6,7,8-tetrahydro-4H-thiazolo[5,4-b]azepines 7, 4,5,6,7,8,9-hexahydrothiazolo[5,4-b]azocine 16 and related compounds were prepared in moderate to good yields from simple diamides, suggesting the wide versatility of the method.
