33315-63-8

Usage

Class

Aromatic ketones

Molar mass

194.18 g/mol

Physical state

White crystalline solid

Odor

Sweet, vanilla-like

Solubility

Soluble in organic solvents (ethanol, acetone)

Uses

Intermediate in pharmaceutical and fragrance compound synthesis, fragrance ingredient in consumer products, food and beverage industry

Upstream product

• 32084-13-2 3-oxo-2-phenyl-acrylic acid methyl ester 
• 2613-89-0 phenylmalonic acid 
• 67-56-1 methanol 
• 1209-80-9 2,6-di-tert-butyl-4-methylphenol potassium salt 
• 101-41-7 benzeneacetic acid methyl ester 
• 37434-59-6 dimethyl 2-phenylmalonate 
• 124-38-9 carbon dioxide 

Downstream Products

• 124-38-9 carbon dioxide 
• 101-41-7 benzeneacetic acid methyl ester 
• 1570-95-2 2-phenylpropane-1, 3-diol 
• 6636-17-5 2,N,N-triphenyl-malonamic acid methyl ester 

Relevant academic research and scientific papers

Cascade Formation of C3-Unsymmetric Spirooxindoles via PhI(OAc)2-Mediated Oxidative C?C/C?N Bond Formation

A series of C3-unsymmetric spirooxindoles were achieved by reaction of diphenylmalonamides with PhI(OAc)2 (PIDA) under metal-free conditions. Control experiments suggest that the hypervalent iodine-mediated reaction undergoes a cascade process involving an oxidative C?C bond formation preceeding an oxidative C?N bond formation. (Figure presented.).

Highly efficient selective monohydrolysis of dialkyl malonates and their derivatives

The highly efficient selective monohydrolysis of symmetric diesters has been applied to monohydrolysis of several dialkyl malonates and their derivatives. The best conditions apply 0.8-1.2 equiv of aqueous KOH with a co-solvent, THF or acetonitrile, at 0 °C. The procedure is highly practical, yielding the corresponding half-esters in high yields in a straightforward manner, without inducing decarboxylation. It was found that the selectivity tends to become higher with increased hydrophobicity.

SYNTHESIS OF HALF ESTERS

A method for hydrolyzing an ester is provided. In accordance with the method, a compound A is provided which has first and second ester moieties. The compound is reacted in a liquid medium with a base having the formula MaXb,such that the first ester moiety is converted to a carboxyl moiety and the second ester moiety remains, wherein the ratio [Xk-]:[A] in the liquid medium is no greater than 1.6, and wherein k > 0.

Anticholinergic compounds, composititons and methods of treatment

Compounds of the formula STR1 wherein the variables are defined in the specification. The compounds and their salts are soft anticholinergic/antisecretory agents especially useful as mydriatics and as antiperspirants.

Process for carboxylating organic substrates with carbon dioxide in hydrocarbon solvents

Carboxylable substrates i.e., ketones, esters, nitroparaffins and nitriles, containing activated hydrogen atoms are carboxylated by reaction with alkaline phenates and CO2 in at least one hydrocarbon solvent selected from aliphatic, alicyclic, aromatic and alkyl-aromatic hydrocarbon solvents.