33342-28-8

Basic information

• Product Name: [5-(4-BROMO-PHENYL)-FURAN-2-YL]-METHANOL
• Synonyms: [5-(4-BROMOPHENYL)-2-FURYL]METHANOL;[5-(4-BROMO-PHENYL)-FURAN-2-YL]-METHANOL;AKOS BB-7849;ASISCHEM T31179;ART-CHEM-BB B025318;RARECHEM AL BD 0799;A3374/0143218;BIM-0041530.P001
• CAS NO: 33342-28-8
• Molecular Formula: C₁₁H₉BrO₂
• Molecular Weight: 253.09
• Mol File: 33342-28-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [5-(4-BROMO-PHENYL)-FURAN-2-YL]-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: [5-(4-BROMO-PHENYL)-FURAN-2-YL]-METHANOL(33342-28-8)
• EPA Substance Registry System: [5-(4-BROMO-PHENYL)-FURAN-2-YL]-METHANOL(33342-28-8)

Safety Data

• Hazardous Substances Data: 33342-28-8(Hazardous Substances Data)

Usage

General Description

The chemical [5-(4-Bromo-phenyl)-furan-2-yl]-methanol is a compound that consists of a furan ring with a 4-bromo-phenyl group attached at the 5-position and a methanol group attached at the 2-position. It is a potentially important organic compound with pharmaceutical and industrial applications. The presence of the bromo-phenyl group suggests that it may have potential bioactive properties, and the furan ring structure imparts aromatic and heterocyclic characteristics. The methanol group provides a hydroxyl functional group, which could contribute to its solubility and reactivity. Overall, this compound has the potential for further exploration in medicinal chemistry and material science for the development of novel drugs and materials.

Upstream product

• 344943-67-5 C₁₈H₁₅ClN₂O₃S 
• 20005-42-9 5-(4-bromophenyl)-2-furancarboxyaldehyde 
• 98-01-1 furfural 
• 88-14-2 2-furanoic acid 
• 52938-96-2 5-(4-bromophenyl)furan-2-carboxylic acid 
• 60335-98-0 5-(4-bromo-phenyl)-furan-2-carbonyl chloride 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 54146-48-4 2-(4-bromo-phenyl)-5-ethoxymethyl-furan 
• 1032338-31-0 C₁₉H₁₂BrCl₂NO₄ 
• 1032338-07-0 C₁₉H₁₂BrF₂NO₄ 
• 20005-42-9 5-(4-bromophenyl)-2-furancarboxyaldehyde 
• 62806-35-3 (E)-3-(5-(4-bromophenyl)furan-2-yl)acrylic acid 
• 176684-12-1 C₁₁H₈BrClO 
• 857048-92-1 2-(4-bromophenyl)-5-[(prop-2-yn-1-yloxy)methyl]furan 

Relevant articles and documents

Synthesis and bioactivity of phenyl substituted furan and oxazole carboxylic acid derivatives as potential PDE4 inhibitors

In this present study, a series of 5-phenyl-2-furan and 4-phenyl-2-oxazole derivatives were designed and synthesized as phosphodiesterase type 4 (PDE4) inhibitors. In vitro results showed that the synthesized compounds exhibited considerable inhibitory ac

2-amino-3-(5-phenylfuran-2-yl)propionic acids and 5-phenylfuran-2-ylacrylic acids are novel substrates of phenylalanine ammonia-lyase

Both racemic 2-amino-3-(5-phenylfuran-2-yl)propionic acids and 5-phenylfuran-2-ylacrylic acids were synthesized and spectroscopically characterized (UV, EI-MS, 1H-NMR and 13C-NMR). The phenyl group of the 5-phenylfuranyl residue carried no (rac-la) para-Br (rac-lb) or Cl para or ortho (rac-lc, d) substituents. The novel furanylalanines were used as substrates of recombinant phenylalanine ammonia-lyase (PAL). When 50% of the racemic 5-phenylfuranylalanines were converted into the corresponding acrylates, the D-enantiomers of the substrates could be isolated. The L-enantiomers could be prepared from the substituted acrylates when the PAL reaction was reversed in the presence of 6 M ammonia at pH 10. The Japan Institute of Heterocyclic Chemistry.

Gold catalysis: Dihydroisobenzofurans and isochromanes by the intramolecular furan/alkyne reaction

A series of furyl alcohols and homofuryl alcohols was synthesized by reduction of furfurals or reaction of furyllithium compounds with epoxides and subsequent propargylation. The gold-catalyzed cycloisomerization of these products furnished dihydroisobenzofurans and isochromanes. Crystal structure analyses proved the sequence of the substituents for both classes of products. Unsaturated dicarbonyl compounds as side-products show the mechanistic relationship to the analogous platinum-catalyzed reactions. Neither ester groups, even on the 4-position of the furan ring, nor aryl bromides hinder the catalysis by gold. In the case of a substrate with an allyl ether in the side chain, a side-product, which provides evidence for a reaction of the alkyne with an inverse regioselectivity, was observed.