54146-48-4

Upstream product

• 64-17-5 ethanol 
• 344943-62-0 4-methylbenzenesulfonyl N'-(5-(4-bromophenyl)furan-2-ylmethylene)hydrazide 
• 33342-28-8 [5-(4-bromophenyl)furan-2-yl]methanol 
• 75-03-6 ethyl iodide 
• 20005-42-9 5-(4-bromophenyl)-2-furancarboxyaldehyde 

Relevant academic research and scientific papers

Synthesis of 5-aryl-2-furaldehyde arylsulfonylhydrazones and their transformations in the Bamford-Stevens reaction

Reactions of arenesulfonohydrazides with 5-aryl-2-furaldehydes in anhydrous ethanol or dioxane afforded a series of the corresponding arylsulfonylhydrazones which reacted with alcoholic sodium alkoxides with liberation of nitrogen and formation of 2-alkoxymethyl-5-arylfurans. Thermolysis of 5-aryl-2-furaldehyde tosylhydrazones in aqueous sodium hydroxide, diethylamine, or morpholine is accompanied by evolution of ～50% of the theoretical amount of nitrogen. The major thermolysis products (yield 70-82%) are 5-aryl-2-furaldehyde N-(5-aryl-2-furylmethyl)tosylhydrazones; also, small amounts (2-3%) of 5-arylfurfuryl alcohols and bis(5-arylfurfuryl) ethers are formed.