33388-23-7

Upstream product

• 98-88-4 benzoyl chloride 
• 2382-96-9 2-sulfanyl-1,3-benzoxazole 
• 2382-96-9 benzo[d]oxazole-2-(3H)-thione 
• 95-55-6 2-amino-phenol 
• 91292-18-1 N,N'carbonyldi<2(3H)-benzoxazolethione> 
• 65-85-0 benzoic acid 
• 81245-06-9 3-(benzoxazol-2-ylthio)-1,2-benzisothiazole 1,1-dioxide 
• 463-71-8 thiophosgene 
• 3743-70-2 N-(2-hydroxyphenyl)benzamide 

Downstream Products

• 13787-59-2 3-benzoyl-2(3H)-benzoxazolone 
• 4457-41-4 4-nitrobenzyl benzoate 
• 80824-77-7 4'-(benzyloxy)benzanilide 
• 15457-50-8 p-benzoylaminophenol 
• 16180-99-7 2-benzamidoethyl benzoate 
• 93-98-1 N-phenyl benzoyl amide 
• 1485-70-7 N-benzylbenzamide 
• 93-99-2 benzoic acid phenyl ester 
• 21011-39-2 3-thiobenzoyl-3H-benzooxazol-2-one 

Relevant academic research and scientific papers

Acylation and alkoxycarbonylation of benzoxazoline-2-thione and benzothiazoline-2-thione

Acylation of benzoxazoline-2-thione (1) and benzothiazoline-2-thione (2) with acetic anhydride (3) and acyl chlorides (4) gave N-acyl (5, 6) and/or S-acyl (7, 8) derivatives depending on the nature of acylating agents and bases used. Alkoxycarbonylation of 1 with aralkyl chlorocarbonates (9) gave N-alkoxycarbonyl derivatives (10) mainly, while that of 2 with aralkyl chloroccarbonates (9) gave S-alkoxycarbonyl derivatives (12) exclusively. Photolysis of N-acyl derivatives (5 or 6) in the presence of alcohols afforded 1 or 2, respectively, together with esters (16).

2(3H)-BENZOXAZOLETHIONE.

A new condensing agent, N,N prime -carbonyldi left bracket 2(3H)-benzoxazolethione right bracket , was readily prepared by the reaction of 2-benzoxazolethiol and trichloromethyl chloroformate in benzene. The condensing agent is shown to be useful for the preparation of amides, esters, and dipeptides under mild conditions. A successful polyamide synthesis by the polycondensation of isophthalic acid with diamines using the condensing agent is also described.