33419-26-0

Basic information

• Product Name: 1-(benzenesulfonyl)ethylsulfonylbenzene
• CAS NO: 33419-26-0
• Molecular Formula: C₁₄H₁₄O₄S₂
• Molecular Weight: 310.395
• Mol File: 33419-26-0.mol

Chemical Properties

• Boiling Point: 548.7°Cat760mmHg
• Flash Point: 364.9°C
• Density: 1.324g/cm³
• CAS DataBase Reference: 1-(benzenesulfonyl)ethylsulfonylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(benzenesulfonyl)ethylsulfonylbenzene(33419-26-0)
• EPA Substance Registry System: 1-(benzenesulfonyl)ethylsulfonylbenzene(33419-26-0)

Safety Data

• Hazardous Substances Data: 33419-26-0(Hazardous Substances Data)

Usage

Chemical family

Organic sulfones

Physical state

White to off-white powder

Melting point

140-143°C

Applications

a. Building block in organic synthesis
b. Production of pharmaceuticals
c. Production of agrochemicals
d. Production of specialty chemicals
e. Plastics and polymers industry
f. Synthesis of novel materials
g. Medicinal chemistry and drug discovery

Safety precautions

Handle with care due to potential hazards if not properly managed

Upstream product

• 10467-10-4 ethylmagnesium iodide 
• 60-29-7 diethyl ether 
• 368-43-4 phenylsulfonyl fluoride 
• 13307-56-7 1,1-bis(phenylthio)ethane 
• 20461-92-1 2,2-bis-phenylsulfanyl-propionic acid 
• 64-17-5 ethanol 
• 3406-02-8 bis(phenylsulfonyl)methane 
• 141-52-6 sodium ethanolate 
• 74-88-4 methyl iodide 
• 105-57-7 diethyl acetal 
• 108-98-5 thiophenol 
• 39837-32-6 bis-benzenesulfonyl-acetic acid ethyl ester 
• 7647-01-0 hydrogenchloride 
• 3561-67-9 bis(phenylthio)methane 

Downstream Products

• 107200-69-1 3-bromo-1-methyl-1,1-butylidene bis(phenyl sulfone) 
• 169689-17-2 (2E,4R)-5,5-bis(phenylsulfonyl)-4-acetoxy-2-hexene 
• 342909-00-6 (4E,3R)-2,2-bis(phenylsulfonyl)-3-acetoxy-6-t-butyldiphenylsilyloxy-4-hexene 
• 342909-04-0 (4E,3R)-2,2-bis(phenylsulfonyl)-3-acetoxy-5-phenyl-4-pentene 
• 38564-57-7 1-Chlor-1,1-diphenylsulfonyl-aethan 
• 342909-33-5 (E,S)-3-phenyl-6,6-bis(phenylsulfonyl)-4-heptenoic acid 
• 342909-32-4 (E,S)-3-methyl-6,6-bis(phenylsulfonyl)-4-heptenoic acid 

Relevant articles and documents

Dynamic Control of Chiral Space Through Local Symmetry Breaking in a Rotaxane Organocatalyst

We report on a switchable rotaxane molecular shuttle that features a pseudo-meso 2,5-disubstituted pyrrolidine catalytic unit on the axle whose local symmetry is broken according to the position of a threaded benzylic amide macrocycle. The macrocycle can

Bis(phenylsulfonyl)methane mediated synthesis of olefins: Via a halogen elimination and double bond migration

An effective dehydrochlorination of bis(phenylsulfonyl)alkane to prepare alkene building blocks is developed. The elimination together with double bond migration results in a variety of β,γ-unsaturated bis(phenylsulfonyl)olefins in good yields with only E geometry. The following chemical diversification represents an easy and straightforward access to a series of alkene building blocks.

Synthesis with sulfones, Part XLIII. Preparation of γ-functionalized vinyl sulfones by nucleophilic substitution of allylidene disulfones; stereospecific reduction of 3-hydroxy-(E)-1-propenyl sulfones to (Z)-allylic alcohols

The substitution of a sulfonyl moiety ao allylidene disulfones by various nucleophiles (PhSNa, PhSO2Na, H2O and R2NH) leads to γ-functionalized (E)-vinyl sulfones.The stereospecific reduction of 3-hydroxy-(E)-1-propenyl sulfones affords (Z)-allylic alcoho