334700-58-2Relevant academic research and scientific papers
Approaches to the synthesis of (+)- and (-)-epibatidine
Barros, M. Teresa,Maycock, Christopher D.,Ventura, M. Rita
, p. 166 - 173 (2001)
Synthetic approaches to the powerful analgesic alkaloids (+)- and (-)-epibatidine are described. The starting material employed was natural (-)-quinic acid from which chiral enones and α-iodoenones were prepared. Stille coupling afforded suitable substrat
