A concise asymmetric synthesis of the marine hepatotoxin 7-epicylindrospermopsin

DOI: 10.1002/anie.200454208

Source and publish data:

Angewandte Chemie - International Edition p. 2930 - 2933 (2004)

Update date:2022-08-04

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Authors:

Looper, Ryan E.

Williams, Robert M.

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Article abstract of DOI:10.1002/anie.200454208

Born from a simple amino acid ... the potent hepatotoxic cyanobacterial alkaloid 7-epicylindrospermopsin (see picture) has been synthesized through a concise asymmetric eighteen-step route. An intramolecular 1,3-dipolar cycloaddition and a nitroaldol reac

Full text of DOI:10.1002/anie.200454208

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