3367-51-9

Basic information

• Product Name: Piperazine, 1,4-bis(4-methoxyphenyl)-
• CAS NO: 3367-51-9
• Molecular Formula: C18H22N2O2
• Molecular Weight: 298.385
• Mol File: 3367-51-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Piperazine, 1,4-bis(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1,4-bis(4-methoxyphenyl)-(3367-51-9)
• EPA Substance Registry System: Piperazine, 1,4-bis(4-methoxyphenyl)-(3367-51-9)

Safety Data

• Hazardous Substances Data: 3367-51-9(Hazardous Substances Data)

Upstream product

• 110-85-0 piperazine 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 100-66-3 methoxybenzene 
• 623-12-1 4-chloromethoxybenzene 
• 104-94-9 4-methoxy-aniline 
• 106-93-4 ethylene dibromide 
• 2933-77-9 N-(2-hydroxyethyl)-4-methoxyaniline 

Relevant articles and documents

Copper-Catalyzed para-Selective C-H Amination of Electron-Rich Arenes

A one-pot two-step method for para-selective C-H amination of carbocyclic arenes comprises the in situ formation of unsymmetrical diaryl-λ3-iodanes followed by their Cu(I)-catalyzed reaction with a range of N-unprotected amines.

Nickel-mediated amination chemistry. Part 2: Selective N-arylation or N,N'-diarylation of piperazine

The 2,2'-bipyridine liganded Ni catalyst has revealed a good selectivity in the mono arylation of piperazine starting from aryl chlorides allowing a selective and efficient synthesis of N-arylpiperazines using stoichiometric amounts of reagents. The preparation of N,N'-diaryl substituted piperazines is also described. (C) 2000 Elsevier Science Ltd.