33682-62-1

Usage

Structure

Heterocyclic organic compound with sulfur and nitrogen in its ring structure

Industrial uses

Production of pharmaceuticals, agrochemicals, and dyes

Potential applications

Materials science, reagent in organic synthesis

Biological activities

Interesting activities making it a potential candidate for drug discovery and development

Upstream product

• 100445-18-9 3,6-dimethylbenzo[d]thiazol-2(3H)-one 
• 99-97-8 Dimethyl-p-toluidine 
• 67-68-5 dimethyl sulfoxide 
• 835872-99-6 N-(2-iodo-4-methylphenyl)methylamine 
• 75-15-0 carbon disulfide 
• 81090-31-5 2-bromo-4-methyl-N-methylaniline 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 29289-13-2 2-iodo-4-methylaniline 

Downstream Products

• 136539-65-6 bis-(5-methyl-2-methylamino-phenyl)-disulfide 

Relevant academic research and scientific papers

A catalyst-free and additive-free method for the synthesis of benzothiazolethiones from: O -iodoanilines, DMSO and potassium sulfide

Under catalyst-free and additive-free conditions, a novel, convenient, eco-friendly method for the synthesis of benzothiazolethiones has been developed. The three-component reaction of o-iodoanilines and K2S with DMSO proceeded smoothly and the corresponding benzothiazolethiones were obtained with good isolated yields. Meanwhile, this method could be used for the synthesis of thioureas from primary diamines. Furthermore, mechanism research showed that DMSO not only functioned as a carbon source, but also as a mild oxidant in this reaction.

Copper-Catalyzed Three-Component Synthesis of Benzothiazolethiones from o-Iodoanilines, Isocyanide, and Potassium Sulfide

An efficient copper catalyzed strategy for the synthesis of a variety of benzothiazolethione derivatives has been developed. In the presence of CuCl, the three-component reaction of o-iodoanilines and K2S with p-toluenesulfonylmethyl isocyanide proceeded smoothly to obtain the corresponding benzothiazolethiones in good to excellent isolated yields. Notably, isocyanide functioned as a carbon source and K2S functioned as a sulfur source in this reaction.

A convenient metal-free method for the synthesis of benzothiazolethiones from o-haloanilines and carbon disulfide

A convenient method has been developed for the preparation of a variety of 1,3-benzothiazole-2(3H)-thiones. The reaction proceeds from an o-haloaniline derivative and carbon disulfide in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene at 80-140 °C to g