3382-62-5

Basic information

• Product Name: 2-{[(4-fluorophenyl)imino]methyl}phenol
• Synonyms: 2-{[(4-fluorophenyl)imino]methyl}phenol;4-Fluoro-N-salicylideneaniline;(E)-2-(((4-Fluorophenyl)imino)methyl)phenol;4-Fluoro-N-salicylideneaniline
• CAS NO: 3382-62-5
• Molecular Formula: C₁₃H₁₀FNO
• Molecular Weight: 215.22
• Mol File: 3382-62-5.mol
• Article Data: 24

Chemical Properties

• Melting Point: 82.0 to 86.0 °C
• Appearance: /
• CAS DataBase Reference: 2-{[(4-fluorophenyl)imino]methyl}phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[(4-fluorophenyl)imino]methyl}phenol(3382-62-5)
• EPA Substance Registry System: 2-{[(4-fluorophenyl)imino]methyl}phenol(3382-62-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 3382-62-5(Hazardous Substances Data)

Usage

General Description

2-{[(4-fluorophenyl)imino]methyl}phenol, also known as 4-Fluorophenyl)imino]methylphenol, is an organic compound with the chemical formula C13H10FNO. It is a yellowish crystalline solid that is commonly used as a reagent in chemical synthesis and as a building block in the production of other compounds. This chemical has potential applications in the pharmaceutical and agrochemical industries, as well as in the production of dyes and pigments. It is important to handle 2-{[(4-fluorophenyl)imino]methyl}phenol with care, as it may be hazardous to health if not used properly.

Upstream product

• 89-95-2 2-methyl-benzyl alcohol 
• 371-40-4 4-fluoroaniline 
• 90-02-8 salicylaldehyde 

Downstream Products

• 102859-02-9 (O)C₆H₄OBOC₆H₄CHNC₆H₄F 
• 84975-15-5 MoCl₂(FC₆H₄NCHC₆H₄O)2 
• 91365-24-1 Nb(OCH(CH₃)2)2(C₆H₄(O)CHNC₆H₄F)3 
• 91365-23-0 Nb(OCH(CH₃)2)3(C₆H₄(O)CHNC₆H₄F)2 
• 91365-22-9 Nb(OCH(CH₃)2)4(C₆H₄(O)CHNC₆H₄F) 
• 1360873-51-3 (3aS,4R,9aR)-N-(4-fluorophenyl)-3,3a,4,9a-tetrahydro-2H-furo[2,3-b]chromen-4-amine 

Relevant articles and documents

Altering the Photochromic Properties of N-Salicylideneanilines Using a Co-Crystal Engineering Approach

In this work photochromic properties of N-salicylideneanilines were modified using a crystal engineering approach. Co-crystallization allowed modification of the structural arrangement and electronic properties of the target compounds altering its photoch

Effect of substituents on the UV spectra of supermolecular system: Silver nanoparticles with bi-aryl Schiff bases containing hydroxyl

Effect of substituents on the ultraviolet (UV) spectra of supermolecular system involving silver nanoparticles (AgNPs) and Schiff bases was investigated. AgNPs and 49 samples of model compounds (MC), bi-aryl Schiff bases containing hydroxyl (XBAY, involving 4-OHArCH?NArY, 2-OHArCH?NArY, XArCH?NAr-4′-OH, and XArCH?NAr-2′-OH), were synthesized. The size of AgNPs was characterized by transmission electron microscopy (TEM), and the UV absorption spectra of AgNPs, XBAYs, and MC-AgNPs mixed solutions were measured, respectively. The results show that (1) the size of AgNPs is larger in MC-AgNPs solutions than that in AgNPs solution due to the distribution of MC molecules on the surface of AgNPs; (2) the UV absorption wavelength of XBAYs changes in the action of AgNPs and their wavelength shift exists limitation between XBAY and MC-AgNPs solutions; and (3) the wavelength shift limit of MC-AgNPs (λWSL) is influenced by the substituents X and Y and the position of hydroxyl OH. The wavenumber ΔνWSL of λWSL can be quantified by employing the excited-state substituent constant σexCC and Hammett constant σ of substituents X and Y. Comparing with the 4-OH, the 4′-OH makes the ΔνWSL a red shift, whereas the 2′-OH, comparing with the 2-OH, makes the ΔνWSL a blue shift.

PdCl2(Ph3P)2/Salicylaldimine Catalyzed Diarylation of Anilines with Unactivated Aryl Chlorides

Triphenylphosphine and salicylaldimine could be used as a mixed ligand system to obtain a high catalytic activity for palladium catalyzed diarylation of primary anilines with unactivated aryl chlorides by the synergistic effect of ligands. The activity and selectivity of the catalytic system could be improved by modifying the structure of salicylaldimine. In refluxing o-xylene, PdCl2(Ph3P)2 with 2,5-ditrifluoromethyl N-phenylsalicylaldimine as a coligand shows high efficiency for the diarylation of various anilines. The catalytic system shows good toleration for the steric hindrance of the substrates. The facile catalytic system works as well on the multiple arylation of 1,1′-biphenyl- 4,4′-diamine with aryl chlorides to afford N,N,N′,N′-tetraaryl-1,1′-biphenyl-4,4′-diamines which are important intermediates of organic light emitting diode (OLED) hole transport materials.