339-26-4

Upstream product

• 75-16-1 methylmagnesium bromide 
• 345-92-6 4,4'-Difluorobenzophenone 
• 75-36-5 acetyl chloride 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 141-78-6 ethyl acetate 

Downstream Products

• 96122-77-9 1-{2-[1,1-Bis-(4-fluoro-phenyl)-ethoxy]-ethyl}-pyrrolidine 
• 133216-83-8 ethyl 5,5-bis(4-fluorophenyl)-2-methyl-4,5-dihydrofuran-3-carboxylate 
• 1335101-73-9 C₁₄H₁₁F₂ 
• 1107605-28-6 C₂₁H₂₄F₂O 
• 1107605-27-5 C₂₃H₂₂F₂O 
• 138534-90-4 Toluene-4-sulfonic acid 2,2-bis-(4-fluoro-phenyl)-ethyl ester 

Relevant academic research and scientific papers

Scandium(III) Trifluoromethanesulfonate Catalyzed Selective Reactions of Donor–Acceptor Cyclopropanes with 1,1-Diphenylethanols: An Approach to Polysubstituted Olefins

An unexpected synthetic approach to polysubstituted olefins through the scandium(III) trifluoromethanesulfonate catalyzed ring-opening reaction of donor–acceptor cyclopropanes with 1,1-diphenylethanols was developed. The reactions, which are experimentally easy to handle, feature tolerance of various functional groups and mild reaction conditions. On the basis of experimental evidence, a plausible mechanism was also proposed.

Base-promoted addition of DMA with 1,1-diarylethylenes: Application to a total synthesis of (-)-sacidumlignan B

A base-promoted addition of DMA (N,N-dimethylacetamide) to 1,1-diarylethylenes has been developed, and it provides a new strategy for the synthesis of N,N-dimethyl-4,4-diarylbutanamides from 1,1-diarylethylenes at room temperature. This method allows us to achieve the goal of synthesizing (-)-sacidumlignan B, and provides simple operation and broad substrate scope by avoiding the use of transition metal catalysts.

Synthesis of 2,2-diarylvinyl phenyl selenides by dehydration of 2-hydroxyalkyl phenyl selenides

A novel route to 2,2-diarylvinyl phenyl selenides is reported by dehydration of the corresponding 2,2-diaryl-2-hydroxyethyl phenyl selenides, prepared by oxyphenylselenenylations of the corresponding 1,1-diarylethylenes, upon treatment with p-toluenesulfonic acid.

Activation conditions play a key role in the activity of zeolite CaY: NMR and product studies of Bronsted acidity

CaY, activated under different conditions, was characterized with 1H, 31P, and 1H/27A] double resonance MAS NMR. The 1H MAS NMR spectra of CaY, calcined in an oven at 500 °C, shows resonances from H2O (bound to Ca2+ and the zeolite framework), CaOH+, aluminum hydroxides, silanols, and Bronsted acid sites. No evidence for Lewis acidity is observed on adsorption of trimethylphosphine, and an estimate of ≈16 Bronsted acid sites per unit cell is obtained for this sample. CaY activated in an oven at higher temperatures contains less water, but all the other species are still present. In contrast, CaY activated by slow ramping of the temperature under vacuum to 500 or 600 °C shows a much lower concentration of Bronsted acid sites (1/unit cell). Again, no evidence for Lewis acidity was observed. These NMR results have been utilized to understand the very different product distributions that are observed for reactions of 1,1- and 1,2-diarylethylenes in zeolite CaY activated in an oven (in air) and under vacuum. Samples with high concentrations of Bronsted acid sites react stoichiometrically with these sites, yielding diarylalkanes. At low concentrations, the Bronsted acid sites can act catalytically resulting in isomerization reactions.