339-27-5

Basic information

• Product Name: Benzene, 1,1'-(difluoromethylene)bis[4-fluoro-
• CAS NO: 339-27-5
• Molecular Formula: C13H8F4
• Molecular Weight: 240.2
• Mol File: 339-27-5.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-(difluoromethylene)bis[4-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(difluoromethylene)bis[4-fluoro-(339-27-5)
• EPA Substance Registry System: Benzene, 1,1'-(difluoromethylene)bis[4-fluoro-(339-27-5)

Safety Data

• Hazardous Substances Data: 339-27-5(Hazardous Substances Data)

Upstream product

• 462-06-6 fluorobenzene 
• 345-92-6 4,4'-Difluorobenzophenone 
• 312-33-4 dichloro-bis-(4-fluoro-phenyl)-methane 

Downstream Products

• 2069-03-6 Difluor-bis-<4-fluor-3-nitro-phenyl>-methan 
• 39144-65-5 methyl 2,2-bis(4-fluorophenyl)acetate 

Relevant articles and documents

The Conversion of Diaryl-1,3-Dithiolanes into gem-Difluoromethylene Compounds by a Combination of Elemental Fluorine and Iodine

Diaryl-1,3-dithiolanes are converted to gem-difluorides in good yield by reaction with a mixture of elemental fluorine and iodine in acetonitrile at room temperature.

Visible-light photoredox-catalyzed selective carboxylation of C(sp3)?F bonds with CO2

It is highly attractive and challenging to utilize carbon dioxide (CO2), because of its inertness, as a nontoxic and sustainable C1 source in the synthesis of valuable compounds. Here, we report a novel selective carboxylation of C(sp3)?F bonds with CO2 via visible-light photoredox catalysis. A variety of mono-, di-, and trifluoroalkylarenes as well as α,α-difluorocarboxylic esters and amides undergo such reactions to give important aryl acetic acids and α-fluorocarboxylic acids, including several drugs and analogs, under mild conditions. Notably, mechanistic studies and DFT calculations demonstrate the dual role of CO2 as an electron carrier and electrophile during this transformation. The fluorinated substrates would undergo single-electron reduction by electron-rich CO2 radical anions, which are generated in situ from CO2 via sequential hydride-transfer reduction and hydrogen-atom-transfer processes. We anticipate our finding to be a starting point for more challenging CO2 utilization with inert substrates, including lignin and other biomass.

Development of triarylamine mediator having ionic-tag and its application to electrocatalytic reaction in ionic liquid

Novel triarylamine (Ar3N) mediators bearing an ionic-tag moiety were synthesized from 4,4′-dibromotriphenylamine. Their electrochemical properties were investigated by cyclic voltammetry both in organic solvent and ionic liquid HF salt. The electrocatalytic reactions such as deprotection and fluorodesulfurization of dithioacetals were successfully carried out using these Ar3N mediators in an undivided cell at room temperature.

Use of Task-Specific Ionic liquid for selective electrocatalytic fluorination

[Chemical equation presented] Highly selective indirect anodic fluorination of organic compounds was successfully carried out for the first time by using a task-specific ionic liquid of iodoarene as a mediator in ionic liquid hydrogen fluoride salts.