33973-12-5

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 20698-91-3 (R)-methyl mandelate 
• 21210-43-5 (S)-Methyl mandelate 
• 4358-87-6 (RS)-methyl mandelate 
• 17199-29-0 (S)-Mandelic acid 
• 611-71-2 (R)-Mandelic Acid 

Downstream Products

• 60168-63-0 R-(-)-2-phenyl-2-(tetrahydropyranyloxy)ethanol 
• 121917-51-9 (R,R)-(-)-1,11-diphenyl-3,6,9-trioxaundecane-1,11-diol 
• 133811-88-8 (4R,14R)-(-)-4,14-diphenyl-3,6,9,12,15-pentaoxa-21-azabicyclo<15.3.1>heneicosa-1(21),17,19-triene 
• 92573-80-3 2-phenyl-2-((tetrahydro-2H-pyran-2-yl)oxy)acetaldehyde 
• 60168-63-0 2-phenyl-<2-oxy>ethanol 
• 110889-05-9 2,2-difluoro-1,4-diphenylbut-3-yn-1-ol 
• 562812-34-4 3-fluoro-2-phenylfuran 
• 31491-37-9 3-fluoro-2,5-diphenyl-furan 
• 958232-01-4 3,3-difluoro-2-phenyl-2,3-dihydrofuran 

Relevant academic research and scientific papers

Au-catalyzed intramolecular hydroalkoxylation of gem-difluorinated alkynols

The intramolecular hydroalkoxylation of gem-difluorinated alkynols was found possible under Au catalysis, allowing for the preparation of a series of fluorinated heterocycles. The nature of the solvent was found to be especially critical in the cyclizatio

OXADIAZOLE BETA CARBOLINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS

Beta-carboline derivatives of structural formula I are selective antagonists of the somatostatin subtype receptor 3 (SSTR3) and are useful for the treatment of Type 2 diabetes mellitus and of conditions that are often associated with this disease, including hyperglycemia, insulin resistance, obesity, lipid disorders, and hypertension. The compounds are also useful for the treatment of depression and anxiety.

Recognition by New Symmetrically Substituted Chiral Diphenyl- and Di-tert-butylpyridino-18-crown-6 and Asymmetrically Substituted Chiral Dimethylpyridino-18-crown-6 Ligands of the Enantiomers of Various Organic Ammonium Perchlorates

Three new chiral pyridino-18-crown-6 ligands have been prepared.These ligands contain either two phenyl, two tert-butyl, or two methyl substituents on chiral macroring carbon atoms.The chiral di-tert-butyl-substituted diester crown analogue was also prepared.The starting chiral di-tert-butyl-substituted tetraethylene glycol needed to prepare the two di-tert-butyl-substituted crowns was obtained from chiral tert-butyl-1,2-ethanediol, which was resolved from its bis(hydrogen phthalate) brucine salt.A high degree of chiral recognition in CD2Cl2 of the enantiomers of ammonium perchlorate (NapEt) was shown by the diphenyl- and di-tert-butyl-substituted crowns as measured by differences in the free energy of avtivation (ΔGc*) values determined by temperature dependent 1H NMR spectroscopy.The diphenyl- and di-tert-butyl-substituted crowns also exhibited high chiral recognition for the enantiomers of NapEt and other chiral organic ammonium salts in methanol and methanol-chloroform mixtures as shown by a large difference in the log K values determined by a direct 1H NMR technique.

Asymmetric Radical Reaction in the Coordination Sphere. 2. Asymmetric Addition of Alkane- and Arenesulfonyl Chlorides to Olefins Catalyzed by a Ruthenium(II)-Phosphine Complex with Chiral Ligands

The addition of arenesulfonyl chlorides to styrene in the presence of a catalytic amount of a ruthenium(II) complex with chiral phosphine ligands, Ru2Cl43 or Ru2Cl43, proceeds under mild conditions to give optically active 1:1 adducts,