3402-84-4

Upstream product

• 578-57-4 2-bromoanisole 
• 1192-96-7 potassium p-cresolate 
• 106-38-7 para-bromotoluene 
• 5633-98-7 potassium guaiacolate 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 90-05-1 2-methoxy-phenol 
• 624-31-7 4-tolyl iodide 
• 6293-68-1 bis(4-methylphenyl)iodonium bromide 
• 106-44-5 p-cresol 
• 5720-05-8 4-methylphenylboronic acid 
• 62790-85-6 tert-Butyl(dimethyl)-(4-methylphenoxy)silane 
• 529-28-2 4-iodoanisol 
• 91-23-6 2-Nitroanisole 

Downstream Products

• 106-44-5 p-cresol 
• 35094-90-7 2-(4-methylphenoxy)phenol 
• 116345-94-9 1-(4-methoxy-3-p-tolyloxy-phenyl)-ethanone 
• 103203-54-9 4-(2-methoxyphenoxy)benzoic acid 

Relevant academic research and scientific papers

Pd-Catalyzed Etherification of Nitroarenes

The Pd-catalyzed etherification of nitroarenes with arenols has been achieved using a new rationally designed ligand. Mechanistic insights were used to design the ligand so that both the oxidative addition and reductive elimination steps of a plausible catalytic cycle were facilitated. The catalytic system established here provides direct access to a range of unsymmetrical diaryl ethers from nitroarenes.

Aromatic ether compound or the sulfhydryl compound

[Problem] Aromatic ether compounds and aromatic sulfide compound of this new technology to[Solution] In general formula (1a), (1b), (1c) palladium or nickel compound or a phosphine compound represented by the compound comprising a transition metal compound in the presence of a transition metal catalyst, (A1) is represented by compounds having hydroxy carbon C a-OH or (A2) with a compound represented by the sulfhydryl carbon C a-SH, nitro group (- NO2 ) To react with an aromatic nitro compound (B), (A1) to the compound of the aromatic nitro compound (C1) or the reaction product of an aromatic ether compounds (B) hetero coupling (A2) of the compounds of the reaction product of an aromatic sulfide compound of an aromatic nitro compound (C2) generating (B) hetero coupling characterized by comprising the step of, aromatic ether compounds or aromatic sulfide compound. [Drawing] no

Oxalic amide ligands, and uses thereof in copper-catalyzed coupling reaction of aryl halides

The present invention provides oxalic amide ligands and uses thereof in copper-catalyzed coupling reaction of aryl halides. Specifically, the present invention provides a use of a compound represented by formula I, wherein definitions of each group are described in the specification. The compound represented by formula I can be used as a ligand in copper-catalyzed coupling reaction of aryl halides for the formation of C—N, C—O and C—S bonds.

Copper-catalyzed Ullmann-type synthesis of diaryl ethers assisted by salicylaldimine ligands

A series of salicylaldimine ligands were designed to promote the copper-catalyzed Ullmann cross-coupling reaction. After a screening process, 2-((2-isopropylphenylimino)methyl)phenol was found to serve as a good supporting ligand for this reaction. Employing this Schiff-base ligand as a new supporting ligand, the copper-catalyzed coupling reactions of aryl bromides and aryl iodides with various phenols successfully proceeded in good yields under mild conditions. Various diaryl ethers were obtained with excellent yields in dioxane in the presence of K3PO4 and a catalytic amount of copper(I) salt.

Methenamine as an efficient ligand for copper-catalyzed coupling of phenols with aryl halides

Employing methenamine as a new supporting ligand, the copper-catalyzed coupling reactions of aryl bromides or aryl iodides with various phenols successfully proceeded in good yields under mild conditions. A series of diaryl ethers were obtained with excellent yields in the presence of K 3PO4 and copper(I) salt. Copyright

Cu-catalyzed arylation of phenols: Synthesis of sterically hindered and heteroaryl diaryl ethers

"Chemical Equation Presentation" Cu-catalyzed O-arylation of phenols with aryl iodides and bromides can be performed under mild condition in DMSO/K3PO4 with use of picolinic acid as the ligand for copper. This method tolerates a variety of functional groups and is effective in the synthesis of hindered diaryl ethers and heteroaryl ethers.

Copper(I) Phenoxide complexes in the etherification of aryl halides

"Chemical Equation Presented" No copping out! Copper(I) phenoxide complexes containing chelating ligands (see picture), proposed intermediates in copper-catalyzed etherification of aryl halides, have been synthesized and fully characterized. The kinetic and chemical competence of the isolated complexes are demonstrated for the synthesis of aryl phenyl ethers, and experiments provide evidence against mechanistic pathways involving the formation of either free or caged radicals.

An efficient BINAM-copper(II) catalyzed Ullmann-type synthesis of diaryl ethers

A wide range of diaryl ethers are synthesized from the corresponding aryl iodides and phenols through Ullmann type coupling reactions in the presence of a catalytic amount of easily available BINAM-Cu(OTf)2 complex under mild reaction conditions. Less reactive aryl bromides have also been shown to react with phenols under identical reaction conditions to give good yields of the diaryl ethers without increasing the reaction temperature and time.

Synthesis of diaryl ethers through the copper-catalyzed arylation of phenols with aryl iodides using KF/Al2O3

An efficient synthesis of diaryl ethers by the copper-catalyzed arylation of phenols with a variety of aryl iodide susing KF/Al2O3 as a suitable base and CuI and 1,3 diphenyl-1,3 propandione as the catalyst is described. Copyright Taylor & Francis Group, LLC.