35094-90-7Relevant academic research and scientific papers
Metal-free oxidative aromatization of 2-aryloxycyclohex-2-en-1-ones to 2-aryloxyphenols using DDQ/Amberlyst-15
Jadhav,Samant
, p. 1301 - 1305 (2015/01/08)
Efficient metal-free oxidative aromatization of 2-aryloxycyclohex-2-en-1-ones was achieved by a combination of 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) and Amberlyst-15. The conditions for oxidative aromatization are mild and applicable for a variety of substrates, and Amberlyst-15 can be successfully recovered and recycled.
Palladium-catalyzed intramolecular C-H arylation of arenes using tosylates and mesylates as electrophiles
Nervig, Christine S.,Waller, Peter J.,Kalyani, Dipannita
, p. 4838 - 4841,4 (2020/09/16)
This paper describes a method for the palladium catalyzed intramolecular C-H arylation using tosylates and mesylates as electrophiles. The transformation is efficient for the synthesis of various heterocyclic motifs including furans, carbazoles, indoles, and lactams. Additionally, a protocol for the one-pot sequential tosylation/arylation of phenol derivatives is presented.
Copper(I) Phenoxide complexes in the etherification of aryl halides
Tye, Jesse W.,Weng, Zhiqiang,Giri, Ramesh,Hartwig, John F.
supporting information; experimental part, p. 2185 - 2189 (2010/06/19)
"Chemical Equation Presented" No copping out! Copper(I) phenoxide complexes containing chelating ligands (see picture), proposed intermediates in copper-catalyzed etherification of aryl halides, have been synthesized and fully characterized. The kinetic and chemical competence of the isolated complexes are demonstrated for the synthesis of aryl phenyl ethers, and experiments provide evidence against mechanistic pathways involving the formation of either free or caged radicals.
O-aryl glucoside SGLT2 inhibitors and method
-
, (2008/06/13)
wherein when Y is or heteroaryl; A is —O(CH2)m, S, —NH(CH2)m, or (CH2)n where n is 0-3 and m is 0-2; and R1 to R6 are as defined herein. A method is also provided for
New preparation of oaryloxyphenols via cyclohexenone oxides
Jung, Michael E.,Starkey, Laurie S.
, p. 7363 - 7366 (2007/10/02)
Reaction of cyclohexenone oxides with phenols under basic two-phase conditions with sonication followed by oxidation represents a new, efficient two-step synthesis of o-aryloxyphenols. I American Chemical Society Arthur C. Cope Scholar, 1995.
Cyclodienones. X. Reaction of Halo-cyclohexadien-1-ones with Phenols in the Presence of α-Picoline and Preparation of 4-Hydroxy- and 2-Hydroxyphenyl Aryl Ethers
Tashiro, Masashi,Itoh, Takashi,Fukata, Gouki
, p. 416 - 420 (2007/10/02)
Reaction of 4-halocyclohexadienones such as 4-bromo-(1a), 4-chloro-2,4,6-tri-t-butyl-(1b), 2,4-dichloro-4,6-di-t-butyl-2,5-cyclohexadien-1-one, and 2,4-dichloro-2,6-di-t-butyl-3,5-cyclohexadien-1-one with phenols in the presence of α-picoline was carried out under various conditions.The reaction of 1a and 1b with phenols afforded the corresponding 2-aryloxy-4,6-di-t-butyl phenols together with various by-products.The AlCl3 catalyzed trans-t-butylation of 2-aroxy-4,6-di-t-butyl-phenols, which were obtained by the above reaction, afforded the corresponding 2-hydroxyphenyl aryl ethers.The similar reaction of 4-aroxy-2,4,6-tri-t-butyl-2,5-cyclohexadien-1-ones also afforded the corresponding 4-hydroxyphenyl aryl ethers.
