3405-93-4Relevant academic research and scientific papers
SMALL MOLECULE CMKLR1 ANTAGONISTS IN INFLAMMATORY DISEASE
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Paragraph 0287, (2020/12/01)
α-NETA analogs are provided for the treatment of inflammatory disease.
Intramolecular Diels-Alder Reactions of Internally-substituted Trienylsulfones. Synthesis of Bicyclo and - Systems Possessing a Bridgehead Sulfonyl Group
Clasby, Martin C.,Craig, Donald,Slawin, Alexandra M. Z.,White, Andrew J. P.,Williams, David J.
, p. 1509 - 1532 (2007/10/02)
A series of trienes possessing internally-activated vinylic sulfone dienophilic groups undergo intramolecular Diels-Alder (IMDA) reaction with high or complete selectivity for the cis-fused products.Incorporation of silyloxy groups within the carbon tethe
Simple Generation of Nonstabilized Azomethine Ylides through Decarboxylative Condensation of α-Amino Acids with Carbonyl Compounds via 5-Oxazolidinone Intermediates
Tsuge, Otohiko,Kanemasa, Shuji,Ohe, Masayuki,Takenaka, Shigeori
, p. 4079 - 4090 (2007/10/02)
Heating α-amino acids with a variety of carbonyl compounds generates N-unsubstituted or N-substituted azomethine ylides of nonstabilized types through the elimination of water and carbon dioxide.The ylides are captured by olefinic, acetylenic, and carbonyl dipolarophiles producing pyrrolidines, pyrrolines, and oxazolidines.The reaction involves intermediary 5-oxazolidinones which can be sometimes isolated.Some synthetic equivalents of parent azomethine ylide, methaniminium methylide, are accessible by this route.
