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Methanone, [4-(2-chloro-4-nitrophenyl)-1-piperazinyl](5-methyl-3-phenyl-4-isoxazolyl)-, commonly known as isoxoprine, is a complex chemical compound belonging to the piperazine derivatives. It has been extensively studied for its potential pharmacological properties, particularly in neuroscience and cardiovascular medicine. Isoxoprine exhibits vasodilatory and antiplatelet effects, making it a promising candidate for the treatment of peripheral vascular diseases. Furthermore, it has been investigated for its ability to improve cerebral blood flow and its anti-inflammatory properties. However, further research is required to fully comprehend the pharmacological effects and safety profile of isoxoprine.

341001-38-5

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341001-38-5 Usage

Uses

Used in Pharmaceutical Industry:
Methanone, [4-(2-chloro-4-nitrophenyl)-1-piperazinyl](5-methyl-3-phenyl-4-isoxazolyl)is used as a vasodilator for the treatment of peripheral vascular diseases. Its vasodilatory and antiplatelet effects contribute to improved blood flow and reduced risk of blood clot formation in the affected areas.
Used in Neurological Applications:
Isoxoprine is used as a potential therapeutic agent for improving cerebral blood flow. Its ability to enhance blood flow in the brain may provide benefits in the treatment of neurological disorders associated with reduced blood flow, such as stroke and cognitive decline.
Used in Anti-inflammatory Applications:
Methanone, [4-(2-chloro-4-nitrophenyl)-1-piperazinyl](5-methyl-3-phenyl-4-isoxazolyl)is used for its potential anti-inflammatory properties. Its ability to modulate inflammatory responses may contribute to the treatment of various inflammatory conditions and reduce the associated symptoms.
Used in Cardiovascular Medicine:
Isoxoprine is used as a potential therapeutic agent in cardiovascular medicine. Its vasodilatory effects may help in the management of hypertension and other cardiovascular conditions by reducing the workload on the heart and improving overall blood circulation.

Check Digit Verification of cas no

The CAS Registry Mumber 341001-38-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,1,0,0 and 1 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 341001-38:
(8*3)+(7*4)+(6*1)+(5*0)+(4*0)+(3*1)+(2*3)+(1*8)=75
75 % 10 = 5
So 341001-38-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H19ClN4O4/c1-14-19(20(23-30-14)15-5-3-2-4-6-15)21(27)25-11-9-24(10-12-25)18-8-7-16(26(28)29)13-17(18)22/h2-8,13H,9-12H2,1H3

341001-38-5 Well-known Company Product Price

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  • Sigma

  • (N2790)  Nucleozin  ≥98% (HPLC), powder

  • 341001-38-5

  • N2790-5MG

  • 1,044.81CNY

  • Detail
  • Sigma

  • (N2790)  Nucleozin  ≥98% (HPLC), powder

  • 341001-38-5

  • N2790-25MG

  • 4,202.64CNY

  • Detail

341001-38-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name [4-(2-chloro-4-nitrophenyl)piperazin-1-yl]-(5-methyl-3-phenyl-1,2-oxazol-4-yl)methanone

1.2 Other means of identification

Product number -
Other names Nucleozin|

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:341001-38-5 SDS

341001-38-5Downstream Products

341001-38-5Relevant academic research and scientific papers

METHANETHIONE COMPOUNDS HAVING ANTIVIRAL ACTIVITY

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Page/Page column 23, (2013/12/03)

A compound of formula (I), The compound is useful as an antiviral agent, in particular for the treatment of influenza. A method for preparing the compound of formula (I) and a composition comprising the compound of formula (I).

ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THERE OF CROSS REFERENCE TO RELATED APPLICATIONS

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, (2011/02/24)

Compounds which exhibit antiviral activity, particularly against influenza virus,and methods of making and using there of are described herein. In one embodiment, the compounds are heterocyclic amides containing piperazine and isozazole rings and optionally substituted with one or more substituents. The compounds can be formulated with one or more pharmaceutically acceptable excipients to form compositions suitable for enteralor parenteral administration. The compounds are preferably used to treat or prevent Influenza Ainfections, such as H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, and H10N7.

ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THEREOF

-

, (2011/09/20)

Compounds which exhibit antiviral activity, particularly against influenza virus, and methods of making and using thereof are described herein. In one embodiment, the compounds are heterocyclic amides containing piperazine and isozazole rings and optionally substituted with one or more substituents. The compounds can be formulated with one or more pharmaceutically acceptable excipients to form compositions suitable for enteral or parenteral administration. The compounds are preferably used to treat or prevent Influenza A infections, such as H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, and H10N7.

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