341497-56-1Relevant articles and documents
Novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 2. Mechanism of inhibition and structure-based improvement of pharmaceutical properties
Liu,Huth,Olejniczak,Mendoza,DeVries,Leitza,Reilly,Okasinski,Fesik,von Geldern
, p. 1202 - 1210 (2001)
The interaction between leukocyte function-associated antigen-1 (LFA-1) and intracellular adhesion molecule-1 (ICAM-1) has been implicated in inflammatory and immune diseases. Recently, a novel series of p-arylthio cinnamides has been described as potent