3416-93-1

Basic information

• Product Name: Benzenamine, 2-(4,5-dihydro-2-oxazolyl)-
• Synonyms: BEN354
• CAS NO: 3416-93-1
• Molecular Formula: C9H10N2O
• Molecular Weight: 162.191
• Mol File: 3416-93-1.mol
• Article Data: 32

Chemical Properties

• Melting Point: 55-56 °C (decomp)
• Boiling Point: 324.8±25.0 °C(Predicted)
• Density: 1.26±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzenamine, 2-(4,5-dihydro-2-oxazolyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-(4,5-dihydro-2-oxazolyl)-(3416-93-1)
• EPA Substance Registry System: Benzenamine, 2-(4,5-dihydro-2-oxazolyl)-(3416-93-1)

Safety Data

• Hazardous Substances Data: 3416-93-1(Hazardous Substances Data)

Upstream product

• 88186-34-9 4,5-dihydro-2-(2-nitrophenyl)oxazole 
• 118-48-9 isatoic anhydride 
• 141-43-5 ethanolamine 
• 870-24-6 2-chloroethanamine hydrochloride 
• 1885-29-6 anthranilic acid nitrile 
• 1570134-74-5 N-(2-(4,5-dihydrooxazol-2-yl)phenyl)-3-fluorobenzamide 
• 1570134-76-7 N-(2-(4,5-dihydrooxazol-2-yl)phenyl)-4-fluorobenzamide 
• 1570134-82-5 4-bromo-N-(2-(4,5-dihydrooxazol-2-yl)phenyl)benzamide 
• 1570134-84-7 N-(2-(4,5-dihydrooxazol-2-yl)phenyl)-2-(trifluoromethyl)benzamide 
• 1570134-86-9 N-(2-(4,5-dihydrooxazol-2-yl)phenyl)-4-(trifluoromethyl)benzamide 
• 1570134-55-2 N-(2-(4,5-dihydrooxazol-2-yl)phenyl)-2-(4-methylphenylsulfonamido)benzamide 
• 1570134-94-9 N-(2-(4,5-dihydrooxazol-2-yl)phenyl)-2-methyl-6-(4-methylphenylsulfonamido)benzamide 
• 1570134-96-1 N-(2-(4,5-dihydrooxazol-2-yl)phenyl)-4-methyl-2-(4-methylphenylsulfonamido)benzamide 
• 1570134-98-3 N-(2-(4,5-dihydrooxazol-2-yl)phenyl)-2,4-dimethyl-6-(4-methylphenylsulfonamido)benzamide 

Downstream Products

• 100135-35-1 [2-(4,5-dihydro-oxazol-2-yl)-phenyl]-carbamic acid ethyl ester 
• 3770-67-0 N-[2-(4,5-dihydrooxazol-2-yl)phenyl]-4-methylbenzenesulfonamide 
• 3416-96-4 N-[2-(4,5-dihydro-thiazol-2-yl)-phenyl]-toluene-4-sulfonamide 
• 101350-98-5 [2-(4,5-dihydro-oxazol-2-yl)-phenyl]-carbamic acid phenyl ester 
• 1204319-30-1 C₁₈H₁₇N₃O₂ 
• 1448644-13-0 5,6-diphenyl-3-[2-(4,5-dihydro-1,3-oxazol-2-yl)phenyl]amino-1,2,4-triazine 
• 21900-42-5 2,4-dimethylbenzoyl chloride 
• 1711-05-3 m-anisoyl chloride 
• 100-07-2 4-methoxy-benzoyl chloride 
• 14002-51-8 4-biphenyl-carboxylic acid chloride 
• 879-18-5 naphthalene-1-carbonic acid chloride 
• 393-52-2 2-Fluorobenzoyl chloride 
• 1711-07-5 3-fluorobenzoyl chloride 
• 403-43-0 4-fluorobenzoyl chloride 

Relevant articles and documents

Rhodium(III)-catalyzed chemodivergent annulations between phenyloxazoles and diazos via C–H activation

Acid-controlled, chemodivergent and redox-neutral annulations for the synthesis of isocoumarins and isoquinolinones have been realized via Rh(III)-catalyzed C[sbnd]H activation. Diazo compounds act as a carbene precursor, and coupling occurs in one-pot process, where adipic acid and trimethylacetic acid promote chemodivergent cyclizations.

Cu-Catalyzed C-H Alkenylation of Benzoic Acid and Acrylic Acid Derivatives with Vinyl Boronates

An efficient Cu-catalyzed C-H alkenylation with acyclic and cyclic vinyl boronates was realized for the first time under mild conditions. The scope of the vinyl borons and the compatibility with functional groups including heterocycles are superior than Pd-catalyzed C-H coupling with vinyl borons, providing a reliable access to multisubstituted alkenes and dienes. Subsequent hydrogenation of the product from the internal vinyl borons will lead to installation of secondary alkyls.

Base-promoted Lewis acid catalyzed synthesis of quinazoline derivatives

A one-pot protocol has been developed for the synthesis of quinazolinones from amide-oxazolines with TsCl via a cyclic 1,3-azaoxonium intermediate and 6π electron cyclization in the presence of a Lewis acid and base. The process is operationally simple and has a broad substrate scope. This method provides a unique strategy for the construction of quinazolinones.