342013-78-9 Usage
Uses
Used in Pharmaceutical Research:
5-BROMO-N-TERT-BUTYLNICOTINAMIDE is used as a research compound for its potential anti-inflammatory and neuroprotective properties, aiding in the study of inflammatory diseases and neurological disorders.
Used in Drug Synthesis:
5-BROMO-N-TERT-BUTYLNICOTINAMIDE is used as a key intermediate in the synthesis of various pharmaceutical drugs, contributing to the development of new treatments for a range of conditions.
Used in Immunomodulation:
5-BROMO-N-TERT-BUTYLNICOTINAMIDE is used as an immunomodulatory agent for its ability to modulate immune responses, which can be beneficial in the treatment of autoimmune and inflammatory conditions.
Used in Neurological Disorder Treatment:
5-BROMO-N-TERT-BUTYLNICOTINAMIDE is used as a potential therapeutic agent for neurological disorders, leveraging its neuroprotective properties to support the health and function of the nervous system.
Used in Inflammatory Disease Management:
5-BROMO-N-TERT-BUTYLNICOTINAMIDE is used as a treatment option for inflammatory diseases, where its anti-inflammatory properties can help manage symptoms and potentially slow disease progression.
Check Digit Verification of cas no
The CAS Registry Mumber 342013-78-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,2,0,1 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 342013-78:
(8*3)+(7*4)+(6*2)+(5*0)+(4*1)+(3*3)+(2*7)+(1*8)=99
99 % 10 = 9
So 342013-78-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H13BrN2O/c1-10(2,3)13-9(14)7-4-8(11)6-12-5-7/h4-6H,1-3H3,(H,13,14)
342013-78-9Relevant academic research and scientific papers
AMINO TRIAZOLES AS PI3K INHIBITORS
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Page/Page column 47, (2009/07/03)
The invention relates to compounds of formula (I) Said compounds are useful as protein kinase inhibitors, especially inhibitors of P13K, for the treatment or prophylaxis of immunological, inflammatory, autoimmune, or allergic disorders. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the production of and use as medicaments.
Unusual sterically controlled regioselective lithiation of 3-bromo-5-(4,4′-dimethyl)oxazolinylpyridine. Straightforward access to highly substituted nicotinic acid derivatives
Robert, Nicolas,Bonneau, Anne-Laure,Hoarau, Christophe,Marsais, Francis
, p. 6071 - 6074 (2007/10/03)
(Chemical Equation Presented) Lithiation of 5-bromonicotinic acid protected as secondary or tertiary amide as well as (4,4′-dimethyl)oxazoline with lithium amides is reported. The unusual C-2 and C-4 regioselective lithiation of 3-bromo-5-(4,4′-dimethyl)oxazolinylpyridine using LTMP versus LDA was observed, providing a new route to substituted nicotinic acid scaffolds. The methodology was applied to the synthesis of novel C-4 and C-6 arylated 5-bromonicotinic acids.
