3427-31-4

Basic information

• Product Name: N-(6-BROMO-BENZOTHIAZOL-2-YL)-2-CHLORO-ACETAMIDE
• Synonyms: N-(6-bromo-1,3-benzothiazol-2-yl)-2-chloroacetamide
• CAS NO: 3427-31-4
• Molecular Formula: C₉H₆BrClN₂OS
• Molecular Weight: 305.58
• Mol File: 3427-31-4.mol
• Article Data: 11

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.83g/cm³
• Refractive Index: 1.741
• CAS DataBase Reference: N-(6-BROMO-BENZOTHIAZOL-2-YL)-2-CHLORO-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(6-BROMO-BENZOTHIAZOL-2-YL)-2-CHLORO-ACETAMIDE(3427-31-4)
• EPA Substance Registry System: N-(6-BROMO-BENZOTHIAZOL-2-YL)-2-CHLORO-ACETAMIDE(3427-31-4)

Safety Data

• Hazardous Substances Data: 3427-31-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H6BrClN2OS/c10-5-1-2-6-7(3-5)15-9(12-6)13-8(14)4-11/h1-3H,4H2,(H,12,13,14)

Upstream product

• 15864-32-1 2-amino-6-bromobenzothiazole 
• 79-04-9 chloroacetyl chloride 
• 63450-94-2 6-bromo-benzothiazol-2-ylamine; hydrobromide 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 1373946-36-1 2-((4-(4,6-bis(3,5-dimethylpiperidin-1-yl)-1,3,5-triazin-2-yl)phenyl)amino)-N-(6-bromobenzo[d]thiazol-2-yl)acetamide 

Relevant articles and documents

An extensive research on aldose reductase inhibitory effects of new 4H-1,2,4-triazole derivatives

Aldose reductase (AR) is a key enzyme, which triggers the excessive accumulation of sorbitol in insulin independent tissues leading to severe diabetes-induced microvascular complications. Substantial evidence has proven that AR inhibition is a well-establ

Efficiently functionalized oxacalix[4]arenes: Synthesis, characterization and exploration of their biological profile as novel HDAC inhibitors

A series of novel substituted oxacalix[4]arene has been synthesized and explored for their biological profile by evaluating anticancer, antifungal and antibacterial properties. The derivatives have been characterized by various spectroscopic techniques su

Access to a new class of biologically active quinoline based 1,2,4-triazoles

As an aspect of our ongoing research in search of new antimicrobial armamentarium, a series of 1,2,4-triazol-3-ylthio-acetamides was constructed and in vitro analyzed for their antimicrobial activity against several bacteria and fungi. Aiming to establish an increased potency, the bioassay results were matched to those of 1,3,4-oxadiazoles, utilized previously. Remarkably, 1,2,4-triazoles were found to possess a good spectrum of antifungal potency, which eventually suggested the azole template as an essential pharmacophore to diversify the biological occupations of the attendant molecules. However, it was noticed that the potency of final analogs against each strain placed reliance on the type of substituent present on benzothiazole ring. The structures of final compounds were confirmed with the aid of IR, 1H NMR, 13C NMR spectroscopy and CHN analysis.