34320-89-3Relevant articles and documents
NIS-TBHP promoted oxidative coupling of C–N and C–O bonds: A metal-free approach to polysubstituted oxazoles
Li, Fei,Liu, Xiaolan,Yang, Shengxiang,Yang, Yuzhu
supporting information, (2020/04/08)
A metal-free approach to polysubstituted oxazoles via the oxidative coupling of readily available benzylamines and 1,3-dicarbonyl derivatives in the presence of an external base has been developed. A variety of functional groups on both of the starting materials are tolerated using this method, affording the corresponding oxazoles in moderate to good yields. Iodination was proposed as the initiation step of the reaction and a plausible mechanism has been proposed to explain the reaction pathway.
Direct one-pot synthesis of zolimidine pharmaceutical drug and imidazo[1,2-a]pyridine derivatives via I2/CuO-promoted tandem strategy
Cai, Qun,Liu, Mei-Cai,Mao, Bi-Ming,Xie, Xuan,Jia, Feng-Cheng,Zhu, Yan-Ping,Wu, An-Xin
, p. 881 - 884 (2015/03/04)
An efficient one-pot synthetic protocol was developed for the synthesis of imidazo[1,2-a]pyridines from easily available starting materials: Aromatic ketones, α,β-unsaturated ketones, β-keto esters and 2-aminopyridines. The present reaction proceeded well in MeOH under the media of I2/CuO. By using this method, the marketed drug zolimidine could be prepared easily with 95% yield. All these target products were characterized by NMR, HRMS and IR spectra. Furthermore, the target compound 3fa was determined by X-ray crystallographic analysis.
Iodine-catalysed sp3 C-H sulfonylation to form β-dicarbonyl sulfones with sodium sulfinates
Gao, Wen-Chao,Zhao, Jin-Jin,Chang, Hong-Hong,Li, Xing,Liu, Qiang,Wei, Wen-Long
, p. 49329 - 49332 (2014/12/10)
An efficient and easily handled method for β-dicarbonyl sulfones with sodium sulfinates as the sulfonyl source was developed. This transformation was involved in the iodine-catalysed sp3 C-H sulfonylation of β-dicarbonyl compounds. This journal
