343322-83-8 Usage
Uses
Used in Pharmaceutical Industry:
2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid ethyl ester is used as a potential drug candidate for the development of new pharmaceuticals with improved efficacy and reduced toxicity. Its unique chemical structure and potential biological activities make it a valuable compound for further research and development in the pharmaceutical field.
Used in Agrochemical Industry:
In the agrochemical industry, 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid ethyl ester is used as a potential component in the development of new agrochemicals. Its diverse chemical structure and potential biological activities can contribute to the creation of more effective and safer agrochemical products.
Used as a Synthesis Intermediate:
2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid ethyl ester also serves as a valuable intermediate in the synthesis of other complex organic compounds. Its unique structure and properties make it a useful building block for the development of novel organic molecules with various applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 343322-83-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,3,3,2 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 343322-83:
(8*3)+(7*4)+(6*3)+(5*3)+(4*2)+(3*2)+(2*8)+(1*3)=118
118 % 10 = 8
So 343322-83-8 is a valid CAS Registry Number.
343322-83-8Relevant academic research and scientific papers
PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME
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, (2008/06/13)
The present invention provides a process for preparing thiazole derivatives of formula (I), that activate the delta subtype of the human Peroxisome Proliferator Activated Receptor (hPPAR δ ), and also provides compounds of formula (II), (IV), (X), (XI) and (XII), intermediate compounds for preparation of the above compounds of formula (I).
A highly efficient synthesis of antiobestic ligand GW501516 for the peroxisome proliferator-activated receptor δ through in situ protection of the phenol group by reaction with a Grignard reagent
Ham, Jungyeob,Kang, Heonjoong
, p. 6683 - 6686 (2007/10/03)
A new synthesis of an agonist for the peroxisome proliferator-activated receptor δ (PPARδ) GW501516 as a potential antiobesity drug is described. The synthetic route involves the in situ protection of the phenol group with a Grignard reagent and a regio-controlled one-pot reaction for the formation of a sulfide bond as the key step. Starting from commercially available 4-iodo-2-methylphenol, this approach affords GW501516 with an overall yield of 87%.
PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME
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Page 18-19, (2008/06/13)
The present invention provides a process for preparing thiazole derivatives of formula (XI), that activate the delta subtype of the human Peroxisome Proliferator Activated Receptor (hPPARδ), and also provides processes for compounds of formula (VI), (VII)
