343322-83-8

Basic information

• Product Name: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid ethyl ester
• Synonyms: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid ethyl ester;ethyl 2-(2-Methyl-4-((4-Methyl-2-(4-(trifluoroMethyl)phenyl)thiazol-5-yl)Methylthio)phenoxy)acetate;ethyl 2-{4-{{2-[4-(trifluoroMethyl)phenyl]-4-Methylthiazol-5-yl}Methylthio}-2-Methylphenoxy}acetate
• CAS NO: 343322-83-8
• Molecular Formula: C₂₃H₂₂F₃NO₃S₂
• Molecular Weight: 481.55
• Mol File: 343322-83-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 563.828 °C at 760 mmHg
• Flash Point: 294.793 °C
• Appearance: /
• Density: 1.34
• CAS DataBase Reference: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid ethyl ester(343322-83-8)
• EPA Substance Registry System: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid ethyl ester(343322-83-8)

Safety Data

• Hazardous Substances Data: 343322-83-8(Hazardous Substances Data)

Usage

General Description

2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid ethyl ester is a chemical compound that belongs to the class of thiazole-based compounds. It is an ethyl ester derivative of phenoxyacetic acid and contains a thiazole ring along with a trifluoromethyl group. 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid ethyl ester has potential applications in pharmaceuticals, agrochemicals, and other industries due to its diverse chemical structure and potential biological activities. It may be used in the development of new drugs or agrochemicals with improved efficacy and reduced toxicity. Additionally, it may also serve as a valuable intermediate in the synthesis of other complex organic compounds. Due to its unique structure and properties, 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid ethyl ester is of interest for further research and development in various fields.

Upstream product

• 317318-96-0 [4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-methanol 
• 72505-21-6 4-trifluoromethylbenzthioamide 
• 439134-78-8 5-(bromomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole 
• 317318-97-1 5-(chloromethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole 
• 60577-30-2 4-iodo-2-methyl-phenol 
• 2362-12-1 4-Bromo-2-methylphenol 
• 105-36-2 ethyl bromoacetate 
• 636589-63-4 4-{{2-[4-(trifluoromethyl)phenyl]-4-methylthiazol-5-yl}methylthio}-2-methylphenol 

Relevant articles and documents

PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME

The present invention provides a process for preparing thiazole derivatives of formula (I), that activate the delta subtype of the human Peroxisome Proliferator Activated Receptor (hPPAR δ ), and also provides compounds of formula (II), (IV), (X), (XI) and (XII), intermediate compounds for preparation of the above compounds of formula (I).

PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME

The present invention provides a process for preparing thiazole derivatives of formula (XI), that activate the delta subtype of the human Peroxisome Proliferator Activated Receptor (hPPARδ), and also provides processes for compounds of formula (VI), (VII)