344249-21-4

Basic information

• Product Name: 2,5-dibromo-p-cresol
• Synonyms: 2,5-dibromo-p-cresol
• CAS NO: 344249-21-4
• Molecular Weight: 265.932
• Mol File: 344249-21-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,5-dibromo-p-cresol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-dibromo-p-cresol(344249-21-4)
• EPA Substance Registry System: 2,5-dibromo-p-cresol(344249-21-4)

Safety Data

• Hazardous Substances Data: 344249-21-4(Hazardous Substances Data)

Upstream product

• 2432-14-6 3,5-dibromo-4-hydroxytoluene 
• 6627-55-0 2-bromo-p-cresol 
• 39953-10-1 2,4,6-tribromo-4-methylcyclohexa-2,5-dienone 
• 7664-93-9 sulfuric acid 
• 50343-63-0 carbonic acid bis-(4-methyl-3-nitro-phenyl ester) 
• 7726-95-6 bromine 
• 7446-70-0 aluminium trichloride 
• 64-19-7 acetic acid 
• 106-44-5 p-cresol 
• 37721-75-8 tetrabromo-p-cresol 
• 36776-51-9 2,3,6-tribromo-4-methyl-phenol 

Downstream Products

• 13979-81-2 3,5-dibromo-4-methylphenol 
• 37721-75-8 tetrabromo-p-cresol 
• 89883-13-6 2,3-dibromo-4-methyl-6-nitrophenol 
• 855156-09-1 3,6-dibromo-2-chloro-4-methyl-phenol 
• 36776-51-9 2,3,6-tribromo-4-methyl-phenol 

Relevant articles and documents

ipso Halogenation. II. Bromination of phenols, isomerisation and disproportionation of bromophenols, and dione-phenol rearrangement of bromodienones

Bromination of p-cresol, bromo-p-cresol, 3,4-dimethylphenol, and mesitol in trifluoromethanesulfonic acid gices as the main product the bromo derivative with bromine meta to hydroxyl, a result attributed to the intermediate formation of a bromodienone and its rearrangement.Phenols does not give m-bromophenol in trifluoromethanesulfonic acid. 4-Bromo-2,4,6-trimethylcyclohexa-2,5-dienone rearranges to 3-bromomesitol in trifluoromethanesulfonic acid and, similarly, 2,4,6-tribromo-4-methylcyclohexa-2,5-dienone rearranges to 3-bromomesitol in trifluoromethanesulfonic acid and, similarly, 2,4,6-tribromo-4-methylcyclohexa-2,5-dienone rearranges to 2,3,6-tribromo-4-methylphenol.Under appropriate conditions debromination of bromodienones is competitive with rearrangement.Tetramethylammonium bromide in trifluoromethanesulfonic acid is an effective reagent for isomerization and disproportionation of bromophenols.Tetramethylammonium iodide in trifluoromethanesulfonic acid is an effective reagent for selective debromination of bromophenols at the ortho and para position.