344305-70-0

Basic information

• Product Name: 5-CHLORO-6-METHOXY-1-INDANONE, 97%
• Synonyms: 5-Chloro-2,3-dihydro-6-methoxy-1H-inden-1-one;[5-CHLORO-6-METHOXY-1-INDANONE, 97%];1H-Inden-1-one, 5-chloro-2,3-dihydro-6-methoxy-;5-Chloro-6-methoxy-indan-1-one;5-Chlor-6-methoxy-1-indanon
• CAS NO: 344305-70-0
• Molecular Formula: C10H9ClO2
• Molecular Weight: 196.63
• Product Categories: C10;Carbonyl Compounds;Ketones
• Mol File: 344305-70-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 165-166℃
• Boiling Point: 340.633°C at 760 mmHg
• Flash Point: 154.17°C
• Appearance: /
• Density: 1.302g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.578
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-CHLORO-6-METHOXY-1-INDANONE, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-6-METHOXY-1-INDANONE, 97%(344305-70-0)
• EPA Substance Registry System: 5-CHLORO-6-METHOXY-1-INDANONE, 97%(344305-70-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-43
• Safety Statements: 37/39
• WGK Germany: 3
• Hazardous Substances Data: 344305-70-0(Hazardous Substances Data)

Usage

Uses

Reactant for:Preparation of azaheterocycles via a palladium(II)-catalyzed ring-expansion reactionPreparation of phenyldihydroindene hydroxy derivatives as dopamine receptor ligands

InChI:InChI=1/C10H9ClO2/c1-13-10-5-7-6(4-8(10)11)2-3-9(7)12/h4-5H,2-3H2,1H3

Upstream product

• 344308-95-8 3-(3-chloro-4-methoxyphenyl)propionyl chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 1857-56-3 3-(3-chloro-4-methoxyphenyl)propionic acid 
• 4903-09-7 3-chloro-4-methoxy-benzaldehyde 

Downstream Products

• 90649-73-3 6-Chlor-indan-5-ol 

Relevant articles and documents

SPIROCOMPOUNDS USEFUL AS MODULATORS FOR DOPAMINE D3 RECEPTORS

The present invention relates to compounds of formula (I) or salts thereof wherein A, X and R4 are defined herein, processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use

Synthesis and antianxiety activity of (ω-piperazinylalkoxy)indan derivatives

A series of (ω-piperazinylalkoxyl)indan derivatives has been synthesized and screened for potential antianxiety activities. The effect of structural modification of these molecules on activities has been systematically examined. Antianxiety activity was displayed by 5-[3-(4-phenyl-1-piperazinyl)propoxy]indan (2), 5-[3-(4-[4-fluorophenyl)-1-piperazinyl]propoxy]indan (8), 6-fluoro-5-[3-(4-phenyl-1-piperazinyl)propoxy]indan (33), and 6-methyl-5-[3-(4-phenyl-1-piperazinyl)propoxy]indan (42), as determined in antifighting and anti-morphine tests. These derivatives in antianxiety tests were equipotent or more potent than chloridazepoxide with less muscle-relaxant effect. They also showed weak neuroleptic-like action.